摘要
目的探讨基于循证药学及PDCA循环建立的重点监控药品合理使用评价模式的应用价值。方法利用医院HIS系统(医院信息系统)对2018年每个季度消耗量排名前10位的重点监控药品:每个药品随机抽取50份病历(每个季度病历总数为500例)进行回顾性分析,其中以第一季度数据作为基于循证药学及PDCA循环建立的重点监控药品合理使用评价模式实施前数据。比较各季度重点监控药品使用不合理情况、患者平均住院天数及重点监控药品比例。结果适应证不适宜、溶媒品种选择不合理、遴选药物不当、溶媒配置不合理(溶媒量不足)、用法用量不合理、用药疗程过长等重点监控药品不合理使用情况显著减少,不合理率由第一季度的26.60%降至第四季度的14.20%(P <0.05),第四季度重点监控药品比例显著低于实施前(P <0.05);同时实施前后患者平均住院天数比较比较,差异无统计学意义(P>0.05)。结论基于循证药学及PDCA循环建立的重点监控药品合理使用评价模式可有效减少重点监控药品的不合理使用现象,提高医院药品管理质量,具有较高的应用价值。
Objective To explore the application value of the evaluation model of rational use of auxiliary drugs based on evidence-based pharmacy and PDCA cycle. Methods The HIS system( Hospital Information System) of the hospital was used to retrospectively analyze the top 10 supplementary drugs consumed in each quarter in 2018: 50 medical records were randomly selected from each drug( 500 cases in total in each quarter). The data of the first quarter were used as the data before the implementation of the evaluation model of rational use of supplementary drugs based on evidence-based pharmacy and PDCA cycle. The irrational use of adjuvant drugs,the average length of hospital stay and the proportion of adjuvant drugs in each quarter were compared. Results The unreasonable use of auxiliary drugs,such as unsuitable indications,unreasonable selection of solvent varieties,improper selection of drugs,unreasonable allocation of solvent( insufficient amount of solvent),unreasonable usage and dosage,and long course of treatment,decreased significantly. The unreasonable rate decreased from26. 60% in the first quarter to 14. 20% in the fourth quarter( P < 0. 05). The proportion of auxiliary drugs in the fourth quarter was significantly lower than that before implementation( P < 0. 05);there was no significant difference in the average hospitalization days of patients before and after the implementation( P > 0. 05). Conclusion The evaluation model of rational use of auxiliary drugs based on evidence-based pharmacy and PDCA cycle can effectively reduce the phenomenon of irrational use of auxiliary drugs,improve the quality of hospital drug management,and has high application value.
作者
梁颖娥
钟慧
蓝晓步
王艳宁
秦艳娥
张慧玲
莫凯
农莉
LIANG Ying'e;ZHONG Hui;LAN Xiaobu(Department of Pharmacy,the First People's Hospital of Nanning,Guangxi Zhuang Autonomous Region,Nanning 530022,China)
出处
《临床合理用药杂志》
2021年第14期1-3,6,共4页
Chinese Journal of Clinical Rational Drug Use
基金
广西壮族自治区卫生和计划生育委员会自筹经费科研项目(No:Z20170041)。
