摘要
目的分析左乙拉西坦治疗小儿癫痫的有效性及不良反应情况。方法该院在2017年8月—2020年6月期间共计收治84例小儿癫痫患儿,将其作为该次观察对象并以数字法分为两组,分别采用奥卡西平(对照组)与联合左乙拉西坦治疗(观察组),对比两组的治疗效果、临床指标及不良反应。结果观察组的治疗有效率为95.24%(40例),高于对照组的76.19%(32例),组间差异有统计学意义(χ^(2)=6.222,P<0.05);观察组治疗后PIQ为(49.12±1.49)分,VIQ为(49.27±1.62)分,FIQ为(99.58±1.33)分,数据较之对照组更高,差异有统计学意义(t=7.146、6.458、9.191,P<0.05);观察组不良反应发生率是4.76%(2例),对照组为23.81%(10例),观察组更低,差异有统计学意义(χ^(2)=6.222,P<0.05)。结论左乙拉西坦治疗小儿癫痫效果良好,且不良反应较少,可以有效促进患儿智商发育,建议在临床中进行推广。
Objective To analyze the effectiveness and adverse reactions of levetiracetam in the treatment of epilepsy in children. Methods A total of 84 cases of pediatric epilepsy were admitted to the hospital from August 2017 to June2020. They were taken as the object of this observation and divided into two groups according to the number method.Oxcarbazepine(control group) and combined Levetiracetam treatment(observation group), compare the treatment effects,clinical indicators and adverse reactions between the two groups. Results The effective rate of treatment in the observation group was 95.24%(40 cases), which was higher than 76.19%(32 cases) in the control group. The difference between the groups was statistically significant(χ^(2)=6.222,P <0.05);PIQ after treatment in the observation group was(49.12±1.49) points, VIQ was(49.27±1.62)points, FIQ was(99.58±1.33) points, the data was higher than the control group, the difference was statistically significant(t=7.146, 6.458, 9.191,P<0.05);the incidence of adverse reactions in the observation group was 4.76%(2 cases), the control group was 23.81%(10 cases), the observation group was even lower, the difference was statistically significant (χ2=6.222,P<0.05). Conclusion Levetiracetam has a good effect in the treatment of children with epilepsy, and has fewer adverse reactions. It can effectively promote the development of children’s IQ, and it is recommended to be promoted in the clinic.
作者
张秀霞
ZHANG Xiuxia(Department of Pediatrics,Juye County People's Hospital,Heze,Shandong Province,274900 China)
出处
《系统医学》
2021年第7期109-111,共3页
Systems Medicine
关键词
左乙拉西坦
小儿癫痫
有效性
不良反应
智商发育
Levetiracetam
Pediatric epilepsy
Effectiveness
Adverse reactions
IQ development
