摘要
目的:观察水火两补汤加减联合优质护理对脾肾气虚型糖尿病肾病(DN)患者的临床疗效。方法:选取78例脾肾气虚型DN患者,按随机数字表法分为对照组和观察组各39例。对照组给予常规治疗和基础护理措施,观察组在对照组基础上给予水火两补汤加减治疗和优质护理。比较2组临床疗效、血糖指标、肾功能指标、简易生活量表(SF-36)评分。结果:观察组和对照组的总有效率分别为89.74%和66.67%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组空腹血糖(FBG)、糖化血红蛋白(HbA1c)、血肌酐(SCr)、血尿素氮(BUN)、24 h尿蛋白定量比较,差异无统计学意义(P>0.05)。治疗后,2组FBG、HbA1c、SCr、BUN、24 h尿蛋白定量均较治疗前降低,且观察组SCr、BUN、24 h尿蛋白定量低于对照组,差异均有统计学意义(P<0.05)。治疗前,2组SF-36各项评分比较,差异无统计学意义(P>0.05)。治疗后,2组SF-36各项评分较治疗前升高,且观察组SF-36各项评分均高于对照组,差异均有统计学意义(P<0.05)。结论:水火两补汤加减联合优质护理治疗脾肾气虚型DN临床疗效显著,可改善患者血糖水平和肾功能,提高患者生活质量。
Objective:To observe the clinical effect of modified Shuihuo Liangbu tang combined with high-quality nursing on diabetic nephropathy(DN) of spleen-kidney qi deficiency type. Methods: A total of 78 cases of DN patients of spleenkidney qi deficiency type were selected and divided into the control group and the observation group according to the random number table method,39 cases in each group.The control group was given routine treatment and basic nursing measures,and the observation group was additionally given modified Shuihuo Liangbu tang and high-quality nursing based on the treatment of the control group.The clinical effect,indexes of blood glucose,indexes of the kidney function,and the score of36-Item Short Form Survey(SF-36) were compared between the two groups. Results:The total effective rate was 89.74%in the observation group, and 66.67% in the control group, the difference being significant(P<0.05). Before treatment,when compared levels of fasting blood glucose(FBG),glycosylated hemoglobin A1 c(HbA1 c),serum creatinine(SCr),blood urea nitrogen(BUN), and 24-hour urine protein between the two groups, there was no significance being found in the difference(P>0.05). After treatment,levels of FBG,HbA1 c,SCr,BUN,and 24-hour urine protein in the two groups were decreased when compared with those before treatment, and levels of SCr, BUN, and 24-hour urine protein in the observation group were lower than those in the control group, differences being significant(P<0.05). Before treatment,there was no significant difference being found in the comparison of each score of SF-36 between the two groups(P>0.05).After treatment,each score of SF-36 in the two groups was increased when compared with that before treatment,and the scores in the observation group were higher than those in the control group, differences being significant(P<0.05).Conclusion:The therapy of modified Shuihuo Liangbu tang combined with high-quality nursing has significant clinical effect in the treatment of DN patients of spleen-kidney qi deficiency type,which can improve the level of blood glucose and the kidney function,and promote quality of life.
作者
方瑜
孟叶彩
FANG Yu;MENG Yecai
出处
《新中医》
CAS
2021年第11期172-175,共4页
New Chinese Medicine
关键词
糖尿病肾病
脾肾气虚型
水火两补汤
优质护理
空腹血糖
糖化血红蛋白
肾功能
简明健康状况量表
Diabetic nephropathy
Spleen-kidney qi deficiency type
Shuihuo Liangbu tang
High-quality nursing
Fasting blood glucose
Glycosylated hemoglobin A1c
Kidney function
36-Item Short Form Survey
