摘要
目的探讨功能康复方案联合艾灸中药透药方案对腰椎间盘突出症(lumbar interal disc hernia,LIDH)患者氧化应激因子水平及功能障碍的改善效果。方法选取焦作市中医院2018年3月至2020年1月收治的88例LIDH患者作为研究对象,将其按照随机数字表分成两组,各44例。对照组常规治疗联合功能康复方案干预,观察组在对照组的基础上联合艾灸中药透药方案干预。比较两组患者治疗疗效、氧化应激因子、血清炎性因子及相关功能障碍评分。结果观察组治疗总有效率95.45%(42/44),对照组治疗总有效率77.27%(34/44),差异有统计学意义(P<0.05)。治疗前两组患者氧化应激因子β-内啡肽(β-ET)、超氧化物歧化酶(SOD)指标水平对比差异无统计学意义(P>0.05);治疗后观察组β-ET、SOD指标水平高于对照组,差异有统计学意义(P<0.05)。治疗前两组患者的肿瘤坏死因子-α(TNF-α)、血清白介素-6(IL-6)指标水平对比差异无统计学意义(P>0.05);治疗后观察组TNF-α、IL-6指标水平低于对照组,差异有高度统计学意义(P<0.001)。治疗前两组患者的视觉模拟评分(VAS)、日本骨科协会腰痛评分(JOA)、Oswestry功能障碍指数问卷评分(ODI)对比差异无统计学意义(P>0.05);治疗后观察组VAS、JOA、ODI评分均低于对照组,差异有高度统计学意义(P<0.001)。结论功能康复方案联合艾灸中药透药方案治疗LIDH的疗效理想,能有效改善氧化应激因子水平,降低炎性因子水平,使患者疾病疼痛、关节功能等得到极大的改善。
Objective To investigate the improvement effect of functional rehabilitation program combined with moxibustion and Chinese medicine penetration program on oxidative stress factor level and dysfunction in patients with lumbar interal disc herniation(LIDH).Methods A total of 88 patients with LIDH admitted to Jiaozuo Hospital of Traditional Chinese Medicine from March 2018 to January 2020 were selected as the research objects,and they were divided into two groups according to the random number table,with 44 patients in each group.The control group received conventional treatment combined with functional rehabilitation program intervention,and the observation group was combined with moxibustion Chinese medicine penetration program intervention on the basis of the control group.The therapeutic efficacy,oxidative stress factors,serum inflammatory factors and related dysfunction scores were compared between the two groups.Results The total effective rate of the observation group was 95.45%(42/44),and that of the control group was 77.27%(34/44),the difference being statistically significant(P<0.05).Before treatment,there was no significant difference in the levels of oxidative stress factorβ-endorphin(β-EP)and superoxide dismutase(SOD)between the two groups(P>0.05).After treatment,the levels ofβ-EP and SOD in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in the levels of tumor necrosis factor-α(TNF-α)and serum interleukin-6(IL-6)levels between the two groups(P>0.05).After treatment,the levels of TNF-αand IL-6 in the observation group were lower than those in the control group,and the difference was highly statistically significant(P<0.001).Before treatment,there was no significant difference in visual analogue score(VAS),Japanese Orthopaedic Association LBP score(JOA)and Oswestry Disability Index questionnaire score(ODI)between the two groups(P>0.05).After treatment,VAS,JOA and ODI scores in the observation group were lower than those in the control group,and the differences were highly statistically significant(P<0.001).Conclusion Functional rehabilitation program combined with combined with traditional Chinese medicine characteristic moxibustion has ideal efficacy in the treatment of LIDH,which can effectively improve the level of oxidative stress factors,reduce the level of inflammatory factors,and greatly improve the patients'disease,pain,joint function and so on.
出处
《中国疗养医学》
2021年第8期825-828,共4页
Chinese Journal of Convalescent Medicine
关键词
腰椎间盘突出症
功能康复锻炼
艾灸
中医
氧化应激因子
炎性因子
功能评分
Lumbar interal disc herniation
Functional rehabilitation exercise
Moxibustion
Traditional Chinese medicine
Oxidative stress factor
Inflammatory factor
Functional score
