摘要
Dear Editor,Middle East respiratory syndrome-related coronavirus(MERS-CoV)is the pathogen responsible for the outbreak of MERS,and we are currently being affected by coronavirus disease 2019(COVID-19)due to infection by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).The S protein of SARS-CoV-2 or MERS-CoV binds angiotensin-converting enzyme 2(ACE2)or dipeptidyl peptidase-4(DPP4),respectively,to facilitate viral particles entry into cells1.The COVID-19 pandemic has caused major socioeconomic disruptions globally.
基金
This work was supported by Hong Kong Research Grant Council(RGC)grants(11101717 and 11103620),NSFC(21778045 and 32070702)
Shenzhen government research grant(JSGG20200225150702770).