摘要
目的:对乳腺癌辅助放射治疗后发生心电图异常的影响因素进行分析。方法:对本院在2018年1月-2020年10月收治的400例需要辅助放疗的乳腺癌患者的临床资料进行回顾性分析,观察其放疗后心电图异常表现,同时通过单因素分析和多因素Logistic回归分析影响其心电图异常的相关因素。结果:400例患者中,放疗后发生心电图异常103例,占比25.75%,其中发生ST-T改变、室性期前收缩、QRS波低电压、心动过速、房性期前收缩、左前分支阻滞及不完全性右束支传导阻滞的例数分别为30、22、15、13、10、7、6例。乳腺癌患者放疗后心电图异常与肿瘤部位、内分泌治疗史无关(P>0.05),与年龄、放疗方式、EPI累积量及基础疾病有关(P<0.05)。多因素Logistic回归分析结果显示,影响患者放疗后心电图异常的独立危险因素为年龄>50岁、电子线放疗、EPI累积量>400 mg及有基础疾病(P<0.05)。结论:乳腺癌患者在辅助放疗后具有较高的心电图异常发生率,其中影响其放疗后心电图异常的独立危险因子为年龄>50岁、电子线放疗、EPI累积量>400 mg及有基础疾病。
Objective:To analyze the influencing factors of abnormal electrocardiogram after adjuvant radiotherapy for breast cancer.Method:The clinical data of 400 patients with breast cancer who needed adjuvant radiotherapy in our hospital from January 2018 to October 2020 were analyzed retrospectively.The abnormal electrocardiogram manifestations after radiotherapy were observed.At the same time,univariate analysis and multivariate Logistic regression analysis were used to analyze the related factors of abnormal electrocardiogram.Result:Among the 400 patients,103 cases had abnormal electrocardiogram after radiotherapy,accounting for 25.75%,including ST-T changes,ventricular extrasystole,QRS wave low voltage,tachycardia,atrial extrasystole,left anterior branch block and incomplete right bundle branch block in 30,22,15,13,10,7,6 cases respectively.The occurrence of abnormal electrocardiogram after radiotherapy of patients with breast cancerwas not significantly related to tumor location and history of endocrine therapy (P>0.05),closely related to age,mode of radiotherapy,EPI accumulation amount and underlying diseases (P<0.05).Multivariate Logistic regression analysis showed that the independent risk factors of abnormal electrocardiogram after radiotherapy were age >50 years old,electronbem radiotherapy,EPI accumulation amount >400 mg and underlying diseases.Conclusion:Breast cancer patients have a high incidence of abnormal electrocardiogram after adjuvant radiotherapy.The independent risk factors affecting abnormal electrocardiogram after radiotherapy are age >50 years old,electronbem radiotherapy,EPI accumulation amount >400 mg and underlying diseases.
作者
梁彩银
LIANG Caiyin(Guangdong Agricultural Reclamation Center Hospital,Zhanjiang 524000,China)
出处
《中外医学研究》
2021年第15期184-187,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
乳腺癌
辅助放疗
心电图异常
影响因素
Breast cancer
Adjuvant radiotherapy
Abnormal electrocardiogram
Influencing factors
