摘要
目的测定不同产地小天冬中重金属及有害元素的含量,并评价其品质。方法采用微波消解-电感耦合等离子体质谱法(ICP-MS)测定小天冬中铅(Pb)、镉(Cd)、汞(Hg)、砷(As)、铜(Cu)的含量。结果按2015年版《中国药典》中部分药材的限量值标准,Cd、As的超标率分别为12.5%、12.5%、Pb、Hg、Cu均符合要求。结论所用方法快速准确、灵敏度高、重复性好,可用于小天冬中重金属及有害元素的含量测定,为其药材中重金属及有害元素限量标准的制定提供了依据。
OBJECTIVE To determine heavy metal and harmful elements content in Asparagus meioclados Levl from different growing areas and quality evaluation.METHODS Microwave digestion method combined with Inductively coupled plasma mass spectrometry method(ICP-MS)was used for the content determination of Pb,Cd,Hg,As and Cu.RESULTS Under the limited value standard of 2015 edition of Chinese Pharmacopoeia,the over-standard rate of heavy metal Cd and As were 12.5%and 12.5%,respectively.The contents of Pb,Hg and Cu conformed to relevant requirements.CONCLUSION The method is fast,accurate,sensitive and repeatable,and can be used for the determination of heavy metals and harmful elements in A.meioclados.It has provided a theoretical basis for the establishment of the limit standard for heavy metal and harmful elements content in the A.meioclados.
作者
张华
麦雅竹
熊学庆
阳文武
ZHANG Hua;MAI Yazhu;XIONG Xueqing;YANG Wenwu(Wanzhou Institute for Food and Drug Control,Chongqing,404000 P.R.China)
出处
《华西药学杂志》
CAS
CSCD
2021年第3期322-324,共3页
West China Journal of Pharmaceutical Sciences
基金
重庆市中药材标准项目(CQZYC201821)。
关键词
小天冬
铅
镉
汞
砷
铜
电感耦合等离子体质谱
微波消解
含量测定
Asparagus meioclados Levl
Pb
Cd
Hg
As
Cu
Inductively coupled plasma mass spectrometry method
Microwave digestion
Determination
