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血液透析联合传统药物治疗难治性心力衰竭的疗效观察

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摘要 目的观察血液透析联合传统药物治疗难治性心力衰竭的疗效。方法选择2018年4月-2019年4月沈阳市沈北新区中心医院收治的难治性心力衰竭患者60例,采用随机盲选法分为观察组和对照组各30例。对照组采用传统药物治疗,观察组采用血液透析联合传统药物治疗,比较2组临床疗效、治疗前后24 h尿量、炎性因子水平及左室射血分数(LVEF)。结果观察组总有效率为93.33%,高于对照组的73.33%,差异有统计学意义(χ^(2)=4.320,P=0.038)。治疗后24 h、48 h,2组24 h尿量均增加,且观察组多于对照组,差异有统计学意义(P <0.05)。治疗后,2组C反应蛋白(CRP)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、肿瘤坏死因子α(TNF-α)及LVEF均优于治疗前(P <0.05),且观察组优于对照组(P <0.05)。结论血液透析联合传统药物治疗难治性心力衰竭的效果较好,可明显改善患者临床症状,值得在临床治疗领域中使用及推广。
作者 李宁宁
出处 《临床合理用药杂志》 2021年第16期58-59,共2页 Chinese Journal of Clinical Rational Drug Use
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