摘要
目的观察外半规管嵴帽型良性阵发性位置性眩晕急性期眼震及残余症状是否对治疗敏感,能否降低其复发。方法纳入2017-09—2019-09安阳地区医院90例外半规管嵴帽型良性阵发性位置性眩晕患者,对照组和治疗组各45例,对照组单纯采用Gufoni手法复位,治疗组在Gufoni手法复位的基础上联合药物治疗,比较2组眼震持续时间,残余症状的持续时间,复发率及复位后当天、第7天、第30天的眩晕障碍量表(DHI)得分。结果治疗组眼震持续时间中位数为4 d,残余症状持续时间中位数为22 d,均明显低于对照组(P<0.01)。治疗组复位结束7 d、30 d的DHI评分逐渐下降,与复位后当天比较差异有统计学意义(P<0.01);与对照组治疗后同一时间段对比,DHI评分差异有统计学意义(P<0.01)。对照组复位结束7 d、30 d的DHI评分逐渐下降,但与复位后当天比较差异无统计学意义(P>0.05)。随访期间,治疗组复发率明显低于对照组(χ^(2)=4.194,P=0.04)。结论Gufoni复位联合药物治疗可明显缩短外半规管嵴帽型良性阵发性位置性眩晕急性期眼震、复位后的残余症状持续时间,降低其复发率。
Objective To explore whether the treatment was effective for nystagmus and residual symptoms of cupulolithiasis of horizontal semicircular canal,and whether the treatment could reduce the recurrence.Methods A randomized control method was used to divide 90 patients with cupulolithiasis of horizontal semicircular canal into control group(n=45)and treatment group(n=45).The control group only used manual reduction,and the treatment group was combined with drug treatment on the basis of manual reduction.The duration of nystagmus,residual symptoms,recurrence rate and the score of Dizziness Handicap Inventory(DHI)were analyzed the same day of reduction and 7 days,30 days after reduction.Results The median duration of nystagmus in the treatment group was 4 days.The median duration of residual symptoms in the treatment group was 22 days.Both of them were significantly shorter than the control group(P<0.01).The DHI score of the treatment group decreased gradually at 7 days and 30 days after reduc⁃tion and the difference was significant compared with that on the day of reduction(P<0.01).The DHI score of the treatment group was significantly different from that of the control group at the same time after reduction(P<0.01).In the control group,the scores of 7 days after reduction and 30 days after reduction decreased,but which was not statistically significant compared with that of the same day of reduction(P>0.05).During the follow-up period,the recurrence rate of the treatment group was significantly lower than that of the control group(χ^(2)=4.194,P=0.04).Conclusion Gufoni maneuver combined with drug treatment can significantly shorten the duration of nystagmus and residual symptoms and reduce recurrence rate of horizontal semicircular canal cupulolithiasis.
作者
李珂
徐辉
LI Ke;XU Hui(Anyang District Hospital of Puyang,Anyang 455000,China;The Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450003,China)
出处
《中国实用神经疾病杂志》
2021年第10期861-866,共6页
Chinese Journal of Practical Nervous Diseases
基金
国家自然科学基金委员会青年基金(编号:81900436)。
关键词
外半规管
嵴帽型耳石症
残余症状
复发率
山莨菪碱
Gufoni复位
Horizontal semicircular canal
Cupulolithiasis
Residual symptoms
Recurrence rate
Anisodamine
Gufoni maneuver
