摘要
Asthma is.a common and recurrent airway inflammatory disorder[1]that mainly presents as chronic arway inflammation.Immunological mechanism plays an important role in asthma occurrence and progression[2].Moreover,the gut is the largest immune organ in the human body and gut microbiota can promote immune system development and immune cell homeostasis regulation.Recent studies have found a new mechanism by which gut microbiota and asthma mutually promote and affect each other[3-5].Gut microbiota activates the mucosal immune system,promotes immune cell migration,and regulates lung immune homeostasis through immune cell metabolites(e.g,short-chain fatty acid)and ligands[6-8].
