摘要
目的研究持续气道正压通气治疗醒后卒中合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的临床效果。方法按照不同的治疗方案,将本院2018年9月至2019年10月接收的104例醒后卒中合并OSAHS患者分为对照组和研究组,对照组(48例)给予常规抗血小板治疗、降压治疗、降脂治疗,同时建议患者夜间睡眠采取侧卧位;研究组(56例)在基础药物治疗上,给予持续气道正压通气(CPAP)。比较两组患者的睡眠质量、智力认知度、焦虑程度、抑郁状况及神经功能等。结果治疗后,两组患者MMSE评分显著高于治疗前,ESS评分显著低于治疗前,且研究组MMSE评分、ESS评分显著优于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者的HAMA、HAMD评分都下降,且研究组显著低于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者的NIHSS评分都下降,且研究组显著低于对照组,差异具有统计学意义(P<0.05)。结论持续气道正压通气治疗醒后卒中合并OSAHS临床效果较好,有效改善患者病情,值得临床推广。
Objective To explore the clinical effect of continuous positive airway pressure(CPAP)in the treatment of post wake stroke with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods According to different treatment plans,104 patients with(OSAHS)received by our hospital from September 2018 to October 2019 were divided into control group and study group.The control group(n=48)was given routine antiplatelet therapy,antihypertensive therapy and lipid-lowering therapy.At the same time,it was suggested that the patients sleep in lateral position at night.The study group(n=56)was treated with basic drugs Continuous positive airway pressure CPAP was given.The sleep quality,intelligence recognition,anxiety,depression and neurological function of the two groups were compared.Results After treatment,MMSE score of the two groups was significantly higher than that before treatment,ESS score was significantly lower than that before treatment,and MMSE score and ESS score of the study group were significantly higher than that of the control group,with a statistically significant difference(P<0.05);after treatment,HAMA and HAMD scores of the two groups were decreased,and the study group was significantly lower than that of the control group,with a statistically significant difference(P<0.05);after treatment The NIHSS score of the two groups decreased,and the difference was statistically significant(P<0.05).Conclusion CPAP is effective in the treatment of OSAHS after wake-up stroke,and it is worth popularizing.
作者
周进
林媛媛
王霞
王阳
王旭
董春瑶
ZHOU Jin;LIN Yuanyuan;WANG Xia;WANG Yang;WANG Xu;DONG Chunyao(Department of Neurology, Shenyang First People's Hospital, Shenyang 110041, China)
出处
《中国老年保健医学》
2021年第3期45-47,共3页
Chinese Journal of Geriatric Care
基金
辽宁省自然科学基金(编号:20180551088)。
