摘要
目的分析重庆市800名教职工健康体检脂肪肝检出情况。方法 2016年~2017年在我院进行健康体检的教职工800名,常规进行腹部超声检查和血生化指标检测,应用Logistic多因素分析脂肪肝发生的因素。结果本组人群脂肪肝检出率为28.4%(227/800),其中男性教职工脂肪肝检出率为39.1%,显著高于女性教职工的20.2%,差异具有统计学意义(P<0.05),40岁以上169例(74.0%),为高发人群,受教育程度为"初中及以下"者脂肪肝检出率为4 2.8%,显著高于"高中或大专"人群的27.7%或"本科以上"人群的23.1%,差异具有统计学意义(P<0.05);脂肪肝组收缩压为(132.3±5.6) mmHg,舒张压为(83.2±10.9) mmHg,BMI为(26.9±3.2) kg/m^(2),空腹血糖为(6.1±1.5) mmol/L,总胆固醇为(5.3±0.9) mmol/L,甘油三酯为(4.2±2.1) mmol/L,尿酸为(361.9±85.9)μmol/L,丙氨酸氨基转移酶为(51.5±5.5) U/L,均显著高于非脂肪肝组【分别为(116.9±23.2) mm Hg、(71.9±9.9) mm Hg、(22.7±2.7) kg/m^(2)、(5.2±1.1) mmol/L、(2.2±1.7) mmol/L、(1.3±0.9) mmol/L、(328.9±213.4)μmol/L和(19.5±4.9) U/L,P<0.05】;Logistic多因素回归分析结果显示,男性、年龄>40岁、初中及以下教育程度、合并高血压和BMI>24 kg/m^(2)均是脂肪肝发生的独立危险因素。结论教职工是脂肪肝的好发人群,了解脂肪肝发生的危险因素,并给予及时、正确的健康教育指导可能对降低发病率有帮助,值得进一步研究。
Objective The aim of this study was to investigate the prevalence of fatty liver on physical healthy examination in 800 faculty in Chongqing. Methods 800 faculty members underwent physical examinations in our hospital between 2016 and 2017. All the individuals received sonography and blood analysis. The Logistic analysis was applied to reveal the risk factors. Results The prevalence of fatty liver was 28.4%( 227/800) in our series,and out of which,the prevalence of fatty liver in male personnel was 39.1%,significantly higher than 20.2% in female( P<0.05),the positive detection as high risk population in individuals greater than 40 year old was 74.0%( 169/227),and the prevalence of fatty liver in uneducated population was 42.8%,significantly higher than 27.7% in educated or 23.1% in well-educated persons( P<0.05);in individuals with fatty liver,the systolic blood pressure was( 132.3 ± 5.6) mm Hg,the diastolic blood pressure was( 83. 2 ± 10. 9) mm Hg,the body mass index( BMI) was( 26.9±3.2) kg/m^(2),the fasting blood glucose was( 6.1±1.5) mmol/L,total blood cholesterol was( 5.3±0.9) mmol/L,the triglycerides was( 4.2±2.1) mmol/L,the uric acid was( 361.9±85.9) μmol/L and serum alanine aminotransferase levels was( 51.5±5.5) U/L,all significantly higher than [( 116.9±23.2) mm Hg,( 71.9±9.9) mm Hg,( 22.7±2.7) kg/m^(2),( 5.2±1.1) mmol/L,( 2.2±1.7) mmol/L,( 1.3±0.9) mmol/L,( 328.9±213.4) μmol/L and( 19.5±4.9) U/L,respectively,P<0.05] in persons without fatty liver;the multivariate Logistic analysis showed than the male,older than 40 years,uneducated,with hypertension and the BMI>24 kg/m^(2) were the independent risk factors for occurrence of fatty liver. Conclusion The prevalence of fatty liver in faculty personnel is high,and the physical examination in time might diagnose the entity early and help give them healthy consultation as early as possible.
作者
李拓键
张超
陈宗涛
Li Tuojian;Zhang Chao;Chen Zongtao(Department of Health Management,First Affiliated Hospital,Military Medical University,Chongqing 400038,China)
出处
《实用肝脏病杂志》
CAS
2021年第4期512-515,共4页
Journal of Practical Hepatology
基金
重庆市卫生和计划生育委员会科研基金资助项目(编号:2016HBRC001)。
关键词
脂肪肝
流行率
体检
教职工
Fatty liver
Prevalence
Health examination
Faculty
