摘要
目的探讨在产妇腰-硬联合麻醉后寒战的治疗中纳布啡的应用价值。方法490例实施剖宫产手术使用腰-硬联合麻醉后发生寒战的产妇,根据随机数字表法分为实验组与对照组,各245例。实验组给予纳布啡,对照组给予盐酸曲马多。对比两组治疗效果、临床症状消失时间、不同时间的镇静评分、不良反应发生情况。结果实验组治疗总有效率96.33%高于对照组的91.84%,差异有统计学意义(P<0.05)。实验组临床症状消失时间为(3.56±1.37)min,短于对照组的(9.85±1.43)min,差异有统计学意义(P<0.05)。给药5 min、手术结束时,实验组镇静评分分别为(4.86±0.31)、(4.63±0.16)分,均高于对照组的(4.59±0.19)、(4.13±0.12)分,差异有统计学意义(P<0.05)。实验组不良反应发生率为10.20%,低于对照组的24.49%,差异有统计学意义(P<0.05)。结论在产妇腰-硬联合麻醉发生寒战后,使用纳布啡对产妇进行治疗,可以有效提高治疗效果,缩短临床症状消失时间,减少不良反应的发生,更有利于产妇的镇静。
Objective To discuss the practical value of nalbuphine on shivering after combined spinal epidural anesthesia.Methods A total of 490 maternal women with shivering after combined spinal epidural anesthesia in cesarean section were divided into experimental group and control group according to random numerical table,with 245 cases in each group.The experimental group was treated with nalbuphine,and the control group was treated with tramadol hydrochloride.The therapeutic effect,disappearance time of clinical symptoms,sedation scores at different time points,and occurrence of adverse reactions were compared between the two groups.Results The total effective rate 96.33%of the experimental group was higher than 91.48%of the control group,and the difference was statistically significant(P<0.05).The disappearance of clinical symptoms(3.56±1.37)min of the experimental group was shorter than(9.85±1.43)min of the control group,and the difference was statistically significant(P<0.05).5 min after medication and at the end of the operation,the sedation score of the experimental group were(4.86±0.31)and(4.63±0.16)points,which were higher than(4.59±0.19)and(4.13±0.12)points of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions of the experimental group was 10.20%,which was lower than 24.49%of the control group,and the difference was statistically significant(P<0.05).Conclusion For maternal women with shivering after combined spinal epidural anesthesia,nalbuphine can effectively improve the treatment effect,shorten the disappearance time of clinical symptoms,reduce the incidence of adverse reactions,and is more conducive to maternal sedation.
作者
周金菊
ZHOU Jin-ju(Dongming Maternal and Child Health and Family Planning Service Center,Heze 274500,China)
出处
《中国实用医药》
2021年第18期117-119,共3页
China Practical Medicine
关键词
纳布啡
产妇
腰-硬联合麻醉
寒战
Nalbuphine
Maternal women
Combined spinal epidural anesthesia
Shivering
