摘要
【目的】研究子宫内膜异位症(endometriosis,EMs)伴不孕症治疗中腹腔镜联合注射用醋酸曲普瑞林的临床治疗效果及其对血浆雌二醇与卵泡刺激素水平的影响。【方法】此次调查研究选取2016年3月至2018年3月在本院接受治疗的EMs伴不孕症的患者160例作为研究对象,并采用随机数字表法分为A组(80例)和B组(80例)。A组采用腹腔镜联合注射用醋酸曲普瑞林进行治疗,B组单一采用腹腔镜治疗方式进行治疗,对两组的治疗有效率、治疗前后的血浆雌二醇(estradiol,E2)、卵泡刺激素(follicle stimulating hormone,FSH)以及总妊娠率。【结果】在总有效率方面,A组为97.50%,B组为87.50%,A组较B组高(P<0.05)。在E2和FSH水平方面,两组治疗前的E2水平和FSH水平无统计学差异(P>0.05)。两组治疗后的E2、FSH均低于治疗前(P<0.05)。A组的E2、FSH水平分别为(41.36±7.53)pmol/L、(6.54±1.82)U/L,B组对应指标的水平为(63.25±5.28)pmol/L、(10.26±1.74)U/L,A组较B组低(P<0.05)。在总妊娠率方面,A组63.75%较B组45.00%高(P<0.05)。【结论】在对EMs伴不孕症患者展开治疗的过程中,采用腹腔镜联合注射用醋酸曲普瑞林进行治疗,其临床效果显著且可以改善血浆雌二醇与卵泡刺激素水平,同时还可以提高妊娠率,值得应用并推广。
【Objective】To study the clinical effect of laparoscopy combined with Tamiflu in the treatment of endometriosis(EMS)with infertility and its effect on the level of estradiol and FSH.【Methods】In this study,160 patients with infertility of EMS who were treated in our hospital from March 2016 to March 2018 were selected as research objects,and were divided into group A(80 cases)and group B(80 cases)by random number table method.Group A was treated by laparoscopy combined with dafelin,and group B was treated by laparoscopy alone.The effective rate,plasma estradiol(E2),follicle stimulating hormone(FSH)and total pregnancy rate were measured before and after treatment.【Results】In terms of total effective rate,group A was 97.50%,group B was 87.50%,and group A was higher than group B(P<0.05).There was no significant difference in E2 and FSH levels between the two groups before treatment(P>0.05).The E2 and FSH in the two groups were lower than those before treatment(P<0.05).The levels of E2 and FSH in group A were(41.36±7.53)pmol/L,(6.54±1.82)U/L,respectively,and those in group B were(63.25±5.28)pmol/L,(10.26±1.74)U/L,respectively,which were lower than those in group B(P<0.05).In total pregnancy rate,63.75%in group A was higher than 45.00%in group B(P<0.05).【Conclusion】In the treatment of endometriosis with infertility,laparoscopy combined with dafelin can improve the level of estradiol and FSH in plasma and pregnancy rate.
作者
黄沁玺
姚德珊
林佳静
李晶晶
HUANG Qin-xi;YAO De-shan;LIN Jia-jing;LI Jing-jing(Department of Obstetrics and Gynecology,Liuzhou Workers Hospital,Liuzhou 545005,China)
出处
《武警后勤学院学报（医学版）》
CAS
2021年第6期1-3,8,共4页
Journal of Logistics University of PAP（Medical Sciences）
基金
国家自然科学基金青年基金项目(81303137)。
