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幼儿母亲贫血相关指标检测的临床意义

Discussion on clinical significance of determination of anemia related items in toddler mothers
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摘要 目的对黑龙江部分地区小学以下阶段的幼儿母亲血样进行分析,统计贫血相关项目,探讨母亲营养情况与年龄的关系以及对孩子的影响。方法收集2019年12月—2020年1月黑龙江部分地区小学以下阶段幼儿母亲的血样,共计399份。采用电化学发光分析仪检测维生素B12(VB12)、叶酸(FOL)、铁蛋白(Fer),采用生化分析仪检测转铁蛋白(TRF);比较不同年龄段受检者上述指标的差异,分析不同指标的异常情况分布;采用双变量相关性分析方法,分析FOL、VB12、Fer、TRF之间的相关性。结果随年龄增长,FOL水平逐渐升高(μg/L:≤22岁组4.40±2.85,23~28岁组4.77±2.66,29~35岁组5.56±3.03,≥36岁组6.37±4.61,各组间比较均P<0.05);FOL缺乏率明显下降〔<22岁组55.56%(20/36),23~28岁组43.84%(64/146),29~35岁组34.55%(57/165),≥36岁组28.85%(15/52),各组间比较均P<0.05〕。FOL与VB12呈明显正相关(r=0.210,P=0.000),FOL与Fer呈明显正相关(r=0.102,P=0.041),Fer与VB12也呈正相关(r=0.155,P=0.002),Fer与TRF则呈明显负相关(r=-0.316,P=0.000)。结论在年轻母亲中FOL缺乏率较高,此类人群的饮食方式与习惯可能对幼儿的营养状况及身体成长造成影响。 Objective To analyze the blood samples from the mothers of children below primary school in some areas of Heilongjiang and detect the items related to anemia,in order to explore the relationship between mothers'nutritional status and age and the effect on children.Methods Totally 399 blood samples from mothers of children below primary school in some areas of Heilongjiang from December 2019 to January 2020 were collected.The levels of vitamin B12(VB12),folic acid(FOL)and ferritin(Fer)were detected by electrochemiluminescence analyzer,and the level of transferrin(TRF)was detected by biochemical analyzer;the differences of above indexes among different age groups were compared,and the abnormal distribution of different indexes was analyzed;the correlation among FOL,VB12,Fer and TRF was analyzed by bivariate correlation analysis.Results With the increase of age,the level of FOL increased(μg/L:≤22 years old 4.40±2.85,23-28 years old 4.77±2.66,29-35 years old 5.56±3.03,≥36 years old 6.37±4.61,all P<0.05);the deficiency ratio of FOL decreased significantly[≤22 years old 55.56%(20/36),23-28 years old 43.84%(64/146),29-35 years old 34.55%(57/165),≥36 years old 28.85%(15/52),all P<0.05].FOL was positively correlated with VB12(r=0.210,P=0.000),FOL was positively correlated with Fer(r=0.102,P=0.041);Fer was positively correlated with VB12(r=0.155,P=0.002)and negatively correlated with TRF(r=-0.316,P=0.000).Conclusion The deficiency ratio of FOL is higher in young mothers.The eating styles and habits of them may affect the nutritional status and physical growth of children.
作者 张明芳 赵楠楠 孙国威 周冰 王清林 Zhang Mingfang;Zhao Nannan;Sun Guowei;Zhou Bing;Wang Qinglin(Heilongjiang Dean Medical Laboratory Co.,Ltd.,Harbin 150000,Heilongjiang,China;Roche Diagnostics(Shanghai)Co.,Ltd.,Harbin 150000,Heilongjiang,China;Department of Nuclear Medicine,the First Affiliated Hospital of Harbin Medical University,Harbin 150000,Heilongjiang,China)
出处 《实用检验医师杂志》 2021年第2期102-104,共3页 Chinese Journal of Clinical Pathologist
关键词 幼儿母亲 营养状况 饮食习惯 发育 Toddler mother Nutritional status Eating habit Puberty
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