摘要
目的:探讨阴道彩超联合血清人绒毛膜促性腺激素(HCG)、孕酮(P)检测对早期异位妊娠的预测价值。方法:回顾性收集本院2017年6月-2019年6月收治的疑似早期异位妊娠孕妇94例临床资料,以诊断性刮宫或病理检查结果为金标准。均经阴道彩超检查及血清HCG、P水平检测并采用ROC曲线评估对早期异位妊娠的预测价值。结果:异位妊娠者子宫内膜厚度(7.36±1.49 mm)小于正常妊娠者(11.19±2.51 mm),阻力指数(0.74±0.18)高于正常妊娠者(0.50±0.12),血清HCG(1655.38±251.36 U/L)、P(20.54±6.88 ng/ml)水平均低于正常妊娠者(3154.67±400.39 U/L、62.39±12.47 ng/ml)(均P<0.05)。ROC曲线分析,阴道超声+HCG+P联合预测早期异位妊娠的AUC最高(0.937),特异度95.7%,灵敏度91.7%,准确度94.7%。结论:阴道超声联合血清HCG、P水平预测早期异位妊娠具有较高价值,可为临床及早发现、确诊、治疗异位妊娠提供可靠依据。
Objective: To investigate the value of transvaginal ultrasound combined with serum human chorionic gonadotropin(hCG) and progesterone(P) levels of women for predicting their early ectopic pregnancy. Methods: The clinical data of 94 pregnant women with suspected early ectopic pregnancy from June 2017 to June 2019 were analyzed retrospectively. The gold standard for diagnosing ectopic pregnancy was based on diagnostic curettage or pathological examination results. These women had all accepted transvaginal ultrasound examination, and serum HCG and P levels detected. ROC curve was used to evaluate the value of transvaginal ultrasound combined with serum HCG and P levels for predicting early ectopic pregnancy. Results: The endometrial thickness(7.36±1.49 mm) of the women with ectopic pregnancy was significant lower than that(11.19±2.51 mm) of normal pregnant women, and the resistance index(0.74±0.18) of the women with ectopic pregnancy was significant higher than that(0.50±0.12) of normal pregnant women. The serum levels of HCG(1655.38±251.36 U/L) and P(20.54±6.88 ng/ml) of the women with ectopic pregnancy were significant lower than those(3154.67±400.39 U/L and 62.39±12.47 ng/ml) of normal pregnant women(all P<0.05). ROC curve analysis showed that the highest AUC, the specificity, the sensitivity and the accuracy of transvaginal ultrasound combined with serum hCG and P levels of women for predicting their early ectopic pregnancy were 0.937, 95.7%, 91.7%, and 94.7%, respectively. Conclusion: Transvaginal ultrasound combined with serum hCG and P levels of women for predicting their early ectopic pregnancy has higher clinical value, which can provide evidences for clinical early finding, diagnosis and treatment of ectopic pregnancy.
作者
叶楠
周琪
YE Nan;ZHOU Qi(Chengdu Women and Children's Center Hospital,Sichuan Province,610091,Chendu women's and children's Center Hospital,School of medicone university of Electronc Sconence and Technology of china)
出处
《中国计划生育学杂志》
2021年第5期1029-1031,1036,F0003,共5页
Chinese Journal of Family Planning
关键词
早期异位妊娠
阴道彩超
人绒毛膜促性腺激素
孕酮
评估
Transvaginal ultrasound
Human chorionic gonadotropin
Progesterone
Early ectopic pregnancy
