摘要
目的:观察通络散浴疗联合隔物灸法治疗铂类药物所致周围神经病变的临床疗效。方法:100例采用随机数字表法分为观察组和对照组各50例。观察组用通络散浴疗联合隔物灸法治疗,对照组用温水浴疗联合隔物灸法治疗。结果:观察组起效时间、外周神经感觉传导速度提升均明显优于对照组(P<0.05),生活质量评分明显改善(P<0.05),肢端麻木、冰凉感症状改善、CIPN分级1级和2级的效果尤为明显(P<0.01)。结论:通络散浴疗联合隔物灸不仅能有效改善铂类化疗药物致CIPN的症状,提高生活质量,还能提高周围感觉神经神经传导速度。
Objective:To observe the clinical efficacy of Tongluo Powder balneotherapy combined with indirect moxibustion in the treatment of peripheral neuropathy caused by platinum drugs.Methods:A total of 100 cases were divided into observation group and control group by random number table method,with 50 cases in each group.The observation group were treated with Tongluo Powder balneotherapy combined with indirect moxibustion while the control group were treated with warm water balneotherapy combined with indirect moxibustion.Results:The onset time and the increase in peripheral nerve sensory conduction velocity of the observation group were significantly better than those of the control group(P<0.05).The quality of life score was significantly improved(P<0.05),especially the improvement of numbness of the limbs and cold sensation symptoms and the effect of CIPN grade 1 and grade 2(P<0.01).Conclusion:Tongluo Powder balneotherapy combined with indirect moxibustion could not only effectively improve the symptoms of CIPN caused by platinum chemotherapy drugs and improve the quality of life,but also increase the nerve conduction velocity of peripheral sensory nerves.
作者
侯妍利
李逸蓝
张国铎
苏立
郭婷婷
胡陵静
冯飞
Hou Yanli;Li Yilan;Zhang Guo duo;Su Li;Guo Tingting;Hu Lingjing;Feng Fei
出处
《实用中医药杂志》
2021年第6期1064-1066,共3页
Journal of Practical Traditional Chinese Medicine
基金
成都中医药大学科技发展基金(YYZX20180030)
重庆市科研院所绩效激励引导专项项目(cstc2018jxj1130005)。
关键词
肺癌
结直肠癌
铂类化疗
周围神经病变
通络散
隔物灸法
Lung cancer
Colorectal cancer
Platinum-based chemotherapy
Peripheral neuropathy
Tongluo Powder
Indirect moxibustion
