摘要
目的探讨多参数磁共振成像-经直肠超声(mpMRI-TRUS)认知融合技术引导前列腺穿刺活检的临床应用价值。方法选取2018年1月-2020年12月就诊于本院且为前列腺癌疑似患者作为研究对象,分为mpMRI-TRUS组与TRUS组。mpMRI-TRUS组所有病例穿刺活检前均行mpMRI检查,根据MRI结果确定靶向病灶,行mpMRI-TRUS认知融合靶向活检和系统10针活检。TRUS组患者只行系统13针活检,比较两组间前列腺癌的检出率,同时比较mpMRI-TRUS组中靶向活检和系统活检在前列腺癌检出率方面的差异,并对穿刺病理结果进行观察和分析。结果mpMRI-TRUS组穿刺活检阳性率为43.59%,TRUS组穿刺活检阳性率为33.07%,两组前列腺癌检出率差异无统计学意义。mpMRI-TRUS组中靶向穿刺的单针阳性率、靶向穿刺组织前列腺癌组织占比高于系统穿刺;mpMRI-TRUS组中靶向穿刺阳性率为38.46%,系统穿刺阳性率为42.30%,两者差异无统计学意义。结论mpMRI-TRUS认知融合技术在前列腺穿刺活检能够以较少的穿刺针数检出前列腺癌,靶向穿刺能提供更多前列腺癌组织,降低前列腺癌穿刺活检的漏诊率。
Objective To explore the clinical application value of multi-parameter magnetic resonance imaging-transrectal ultrasound(mpMRI-TRUS)cognitive fusion technology to guide targeted prostate biopsy.Methods The research objects were patients suspected of prostate cancer from January 2018 to December 2020 and the patients were divided into mpMRI-TRUS group and TRUS group.All cases in the mpMRI-TRUS group underwent mpMRI examination before needle biopsy.The targeted lesions were determined according to the MRI results.And mpMRI-TRUS cognitive fusion targeted biopsy and system 10-needle biopsy were performed.Patients in the TRUS group only underwent a systematic 13-needle biopsy.The detection rate of prostate cancer between the two groups was compared.At the same time,the difference in the detection rate of targeted biopsy and systematic biopsy in the mpMRI-TRUS group was also compared.The pathological results of puncture were observed and analyzed.Results The positive rate of needle biopsy in the mpMRI-TRUS group was 43.59%,and the TRUS group was 33.07%.There was no significant difference in the detection rate of prostate cancer between the two groups.In the mpMRI-TRUS group,the single-needle positive rate and the proportion of prostate cancer tissue were higher than that of system puncture.The positive rate of targeted puncture in the mpMRI-TRUS group was 38.46%,and the system puncture was 42.30%.The difference between the two groups is not statistically significant.Conclusion The mpMRI-TRUS cognitive fusion technology can detect prostate cancer with fewer needles in prostate biopsy.Targeted biopsy puncture can provide more prostate cancer tumor tissues and reduce the missed diagnosis rate of prostate cancer biopsy.
作者
区文财
何尚鹏
梁宇翔
邱春花
OU Wencai;HE Shangpeng;LIANG Yuxiang;QIU Chunhua(Department of ultrasound,Guangzhou First People's Hospital,Guangzhou 510180,China;Department of Urology,Guangzhou First People's Hospital,Guangzhou 510180,China)
出处
《广州医药》
2021年第4期77-79,99,共4页
Guangzhou Medical Journal
基金
广东省自然科学基金(2018A030313668)。
