摘要
1例学龄期男童因“反复感染3年余”于2020年3月5日入院。临床诊断为“免疫缺陷病、巨细胞病毒视网膜炎(CMVR)”,治疗至入院第10周,患儿眼部病变较前加重,房水中巨细胞病毒载量明显升高,医师考虑眼部感染复发。临床药师分析后建议在更昔洛韦联合膦甲酸钠静脉滴注的基础上行玻璃体腔内注射治疗。经积极治疗后,患儿视力改善,房水中病毒载量下降,病情好转。临床药师参与儿童免疫缺陷、CMVR复发情况下的抗感染治疗方案制定,与医生、护士、患儿及家属有效沟通,充分发挥了药师在多学科治疗团队中的作用。
A school-age boy was hospitalized on March 5^(th),2020 due to repeated infection for more than 3 years.The clinical diagnoses were immunodeficiency,cytomegalovirus retinitis(CMVR).At the 10^(th)week of admission,his ocular lesions aggravated and the cytomegalovirus load in the aqueous humor significantly increased.The doctor considered the recurrence of eye infection.Clinical pharmacists suggested giving ganciclovir combined with foscarnet sodium by intravenous infusion and intravitreal injection after detailed analysis.His vision improved and the viral load in the aqueous humor decreased after treatment.Clinical pharmacists participated in the formulation of anti-infection treatment plan for children with immunodeficiency and CMVR recurrence,effectively communicated with doctors,nurses,patient and his parents,thus to fully played the role of pharmacists in the multidisciplinary treatment team.
作者
杨梅
王晓玲
YANG Mei;WANG Xiao-ling(National Children's Medical Center/Department of Pharmacy,Beijing Children's Hospital Affiliated to Capital Medical University,Beijing 100045,China)
出处
《中国药物应用与监测》
CAS
2021年第3期168-170,共3页
Chinese Journal of Drug Application and Monitoring
基金
中国医学科学院医学与健康科技创新工程项目(2019-I2M-5-026)
儿童感染免疫相关疾病精准诊断体系建立及精准治疗研究(XTZD20180504)。
关键词
免疫缺陷
巨细胞病毒视网膜炎
儿童
临床药师
药学监护
Immunodeficiency
Cytomegalovirus retinitis
Children
Clinical pharmacist
Pharmaceutical care
