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血清铁调素在肾性贫血中的研究进展 被引量:1

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摘要 铁调素最早被PARK等^([1-2])学者从尿液及血清中提取发现,是一种在肝脏中合成的具有广泛抗菌活性^([4])的小分子多肽,经肾脏排泄。食物中的Fe^(3+)在体内被还原成Fe^(3+),Fe^(2+)通过与二价金属离子转运蛋白和肠细胞色素B结合进人细胞内被肠道吸收和储存,细胞内一部分Fe^(2+)与膜铁转运蛋白(FPN)结合进入血液循环,氧化为Fe^(3+)后与转铁蛋白结合,最终被输送至机体各个组织细胞。
出处 《浙江临床医学》 2021年第7期1063-1065,共3页 Zhejiang Clinical Medical Journal
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