摘要
目的探讨肇庆市10年内200例先天性甲状腺功能减低症(congenital hypothyroidism,CH)治疗效果。方法选取2018年5月—2020年4月在肇庆辖区内近10年运用新生儿筛查技术筛查确诊并跟踪治疗的CH患儿200例作为研究对象,按照随机数字表法分成观察组和对照组各100例,对照组采用常规治疗管理,观察组采用个体化追踪治疗管理,比较两组患儿生长发育、智能发育、学习成绩的影响情况。结果在身高、体质量、头围等生长发育指标上,两组患儿干预后较干预前均明显增加(P<0.05),观察组明显高于对照组(P<0.05);在全智商(full intelligence quotient,FIQ)、操作智商(performance intelligence quotient,PIQ)、言语智商(verbal intelligence quotient,VIQ)、大运动发育商(developmental quotient,DQ)、精细动作DQ、适应能力DQ、言语能DQ、社交行为DQ等智能发育上,两组患儿干预后较干预前均明显提高(P<0.05),观察组明显高于对照组(P<0.05);在学习成绩上,观察组明显高于对照组(P<0.05)。结论CH患儿采用个体化追踪治疗管理有显著效果,能够促进患儿的生长、智能发育及学习成绩。
Objective To investigate the therapeutic effect of 200 cases of congenital hypothyroidism(CH)in Zhaoqing city in 10 years.Methods From May 2018 to April 2020 in Zhaoqing prefecture in recent 10 years with neonatal screening technology screening diagnosis and follow up treatment of children with CH 200 cases as the research object,according to the random number table method the patients were divided into the observation group and the control group,100 cases in the control group was used conventional treatment management,the observation group was treated by individual track management,compared two groups of children with growth,intelligence development,the influence of the learning situation.Results In terms of growth and development indexes,such as height,weight and head circumference,the two groups were significantly increased after intervention compared with before intervention(P<0.05),the observation group was significantly higher than the control group(P<0.05).In terms of intelligence development,such as total intelligence(FIQ),operational intelligence(PIQ),verbal intelligence(VIQ),gross motor developmental quotient(DQ),fine motor DQ,adaptive ability DQ,speech ability DQ and social behavior DQ,the two groups were significantly increased after intervention compared with before intervention(P<0.05),and the observation group was significantly higher than the control group(P<0.05).In terms of academic performance,the observation group was significantly higher than the control group(P<0.05).Conclusion Individualized follow-up treatment and management for CH children has significant effects,can promote the growth,intelligence development and academic performance of CH children.
作者
陈丽华
陈志玮
黄锶
郑宏基
CHEN Lihua;CHEN Zhiwei;HUANG Si;ZHENG Hongji(Department of Child Health,Zhaoqing Second People’s Hospital,Zhaoqing Guangdong 526060,China)
出处
《中国卫生标准管理》
2021年第13期38-42,共5页
China Health Standard Management
关键词
先天性甲状腺功能减低症
智能发育
生长发育
个体化追踪
新生儿疾病筛查
左旋甲状腺素钠
congenital hypothyroidism
intelligent development
growth and development
individualized follow-up
screening for neonatal disease
levothyroxine sodium
