摘要
生物可降解血管支架相较于药物洗脱支架,具有更优良的生物相容性,且术后待血管完成重建,恢复正常生理功能后降解,不会长期留存体内导致晚期支架内血栓,不需要长期服用抗排斥药物等优点,成为人们在治疗心脑血管堵塞疾病关注的焦点。该文对生物可降解血管发展历程和几种不同材质血管支架在体(动物体或人体)研究现状进行综述,指出了目前所存在的问题,并对生物可降解血管支架研究方向作出预测。
Biodegradable vascular stents have better biocompatibility than drug-eluting stents.The blood vessels are rebuilt and degraded after normal physiological functions are restored.Due to it will not stay in the body for a long time and the patients don’t need taking anti-rejection drugs all the time,it becomes the focus of attention in the treatment of coronary heart disease.This article introduced the development history of biodegradable stents and reviewed the research status of several different materials of vascular stents(animals or humans)in vivo and pointed out the existing problems.And it also predicted the research direction of biodegradable vascular stents.
作者
王洋洋
吴红枚
甄文强
龚韬
李端
蔡垚
范诗易
WANG Yangyang;WU Hongmei;ZHEN Wenqiang;GONG Tao;Li Duan;CAI Yao;FAN Shiyi(College of Chemistry and Chemical Engineering,University of South China,Hengyang,421000)
出处
《中国医疗器械杂志》
2021年第4期410-415,共6页
Chinese Journal of Medical Instrumentation
基金
国家自然科学基金(21104031)。
