摘要
目的探讨布拉氏酵母菌散联合聚乙二醇及摩腹疗法治疗小儿功能性便秘的效果。方法回顾性分析我院2018年1月~2019年12月收治的124例小儿功能性便秘患者作为研究对象,随机分为对照组和实验组,各62例。对照组采用聚乙二醇+摩腹疗法治疗,实验组在此基础上加用布拉氏酵母菌散治疗,比较两组治疗总有效率、临床症状改善时间、不良反应发生率及大便性状评分。结果治疗1个月后,对照组总有效率为67.74%,低于实验组的79.03%,但差异无统计学意义(P>0.05),治疗2个月后,对照组总有效率为70.96%,低于实验组的85.48%,差异有统计学意义(P<0.05);实验组腹胀、哭闹/便痛消失时间短于对照组,差异有统计学意义(P<0.05),两组便秘、排便困难消失时间比较,差异无统计学意义(P>0.05);实验组不良反应发生率低于对照组,差异有统计学意义(P<0.05);两组治疗1月后大便性状评分均有所改善,但组间比较差异无统计学意义(P>0.05),治疗2个月后实验组大便性状评分优于对照组,差异有统计学意义(P<0.05)。结论布拉氏酵母菌散联合聚乙二醇及摩腹疗法治疗小儿功能性便秘简单、易行、安全,临床疗效可靠,是治疗小儿功能性便秘的一种可行的方法。
Objective To explore the effect of Saccharomyces Boulardii Sachets combined with Polyethylene Glycol and abdominal massage therapy in the treatment of children with functional constipation.Methods A retrospective analysis of 124 pediatric patients with functional constipation admitted to our hospital from January 2018 to December 2019 as the research objects were randomly divided into a control group and an experimental group,with 62 cases in each group.The control group was treated with Polyethylene Glycol+abdominal massage therapy,and the experimental group was treated with Saccharomyces Boulardii Sachets on this basis.The total effective rate of treatment,the time to improve clinical symptoms,the incidence of adverse reactions and the scores of stool traits were compared between the two groups.Results After 1 month of treatment,the total effective rate of the control group was 67.74%,which was lower than 79.03%of the experimental group,but the difference was not statistically significant(P>0.05).After 2 months of treatment,the total effective rate of the control group was 70.96%,which was lower than 85.48%of the experimental group,the difference was statistically significant(P<0.05);The disappearance time of abdominal distension,crying/defecation pain in the experimental group was shorter than that in the control group,the difference was statistically significant(P<0.05).There was no statistically significant difference in the disappearance time of constipation and defecation difficulties between the two groups(P>0.05);The incidence of adverse reactions in the experimental group was lower than that in the control group,the difference was statistically significant(P<0.05);Stool traits scores in the two groups improved after 1 month of treatment,but the difference between the groups was not statistically significant(P>0.05).After 2 months of treatment,the scores of stool traits in the experimental group were better than those in the control group,the difference was statistically significant(P<0.05).Conclusion The combination of Saccharomyces Boulardii Sachets combined with Polyethylene Glycol and abdominal massage therapy is simple,easy,and safe to treat children with functional constipation.The clinical effect is reliable.It is a feasible method for the treatment of children with functional constipation.
作者
连娇燕
陈颢予
蒋成鹏
王宝林
周丽
徐晓红
LIAN Jiao-yan;CHEN Hao-yu;JIANG Cheng-peng;WANG Bao-lin;ZHOU Li;XU Xiao-hong(Department of Pediatric Digestive Infection,Gansu Maternal and Child Health Hospital,Lanzhou 730060,Gansu,China)
出处
《医学信息》
2021年第15期172-174,共3页
Journal of Medical Information
关键词
聚乙二醇
布拉氏酵母菌散
摩腹
小儿功能性便秘
排便困难
Polyethylene glycol
Saccharomyces Boulardii Sachets
Abdominal massage therapy
Functional constipation in children
Difficulty defecation
