摘要
玫瑰痤疮是一种常见的慢性面部皮肤炎症,其具体发病机制目前尚未完全阐明。临床和基础的研究提示该病主要与遗传、免疫及神经血管功能紊乱密切相关,外界中如微生物、紫外线等诱发因素可以诱发并加重疾病,这些发病因素可以单独也可以共同参与疾病的发生。本文就近期有关玫瑰痤疮发病机制的研究进展进行总结,以期为今后进一步的疾病研究提供参考。
Rosacea is a common and chronic facial inflammation skin disease.The precise pathogenesis of rosacea has not been fully elucidated.It is suggested that genetic,immune and neurovascular disorders are closely related to the disease,and external factors including microorganisms and ultraviolet rays can induce and aggravate rosacea.These factors usually participate in the occurrence of rosacea alone or together.This paper summarized and analyzed its pathogenesis.
作者
袁新
汪犇
邓智利
谢红付
李吉
YUAN Xin;WANG Ben;DENG Zhili;XIE Hongfu;LI Ji(Department of Dermatology,Guizhou Provincial People's Hospital,Guiyang 550002,China;Department of Dermatology,Xiangya Hospital,Central South University,Changsha 410008,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2021年第8期943-948,共6页
The Chinese Journal of Dermatovenereology
基金
国家自然科学基金项目(82073457)
贵州省科技计划项目(黔科合基础-ZK[2012]一般421)。
关键词
玫瑰痤疮
遗传
免疫
神经血管
皮肤屏障
微生物
紫外线
Rosacea
Genetics
Immunity
Neurovascular
Skin barrier
Microorganism
Ultraviolet
