摘要
目的:观察养血解毒汤联合中药药浴对血燥型银屑病的临床疗效。方法:选取首都医科大学附属北京中医医院、北京中医药大学第三附属医院80例血燥型银屑病患者,依照随机数字表法分为观察组和对照组,每组40例。对照组口服养血解毒汤,观察组在对照组的基础上联合中药药浴,两组均治疗8周,8周后对比两组临床疗效,观察患者皮损体表面积(BSA)、严重程度指数(PASI评分)、皮肤瘙痒程度(VAS)及皮肤病生活质量指数(DLQI)变化。结果:治疗8周后,观察组总有效率90.0%(36/40)显著高于对照组70.0%(28/40)(P<0.05);两组BSA、PASI、VAS、DLQI评分均较治疗前显著降低(P<0.05),且观察组显著低于对照组(P<0.05)。结论:养血解毒汤联合中药药浴治疗血燥型银屑病临床疗效较单用养血解毒汤好,能有效改善患者皮损面积、严重程度、瘙痒症状及生活质量,可用于临床推广、深入研究。
Objective:To analyze clinical efficacy of Yangxue Jiedu Decoction combined with traditional Chinese medicine bath on psoriasis of blood dryness syndrome.Methods:Selected 80 cases of patients with psoriasis of blood dryness syndrome and divided them into the observation group and the control group according to random number table,40 cases in each group.The control group were treated with Yangxue Jiedu Decoction.The observation group were treated with Yangxue Jiedu Decoction combined with traditional Chinese medicine medicated bath.Both groups were treated for 8 weeks.After 8 weeks,compared the clinical effects of the two groups and observed the score changes in the skin surface area(BSA),psoriasis area and severity index(PASI),degree of skin itching(VAS)and the dermatological quality of life index(DLQI).Results:After 8 weeks of treatment,the total effective rate of the observation group was 90.0%(36/40),which was higher than that of the control group(70.0%,28/40)(P<0.05).The BSA,PASI,VAS,and DLQI scores of the observation group and the control group were lower than before treatment(P<0.05).The BSA,PASI,VAS and DLQI score of the observation group was significantly lower than that of the control group(P<0.05).Conclusion:Yangxue Jiedu Decoction combined with traditional Chinese medicine medicine bath has a significant clinical effect on psoriasis of blood dryness syndrome,which can improve the skin lesion area,the severity of skin lesions,the symptoms of itching and the quality of life of patients.It can be used for clinical promotion and in-depth study.
作者
吕景晶
韩晓丽
孙雯雯
齐聪
刘青武
鲍身涛
LYU Jing-jing;HAN Xiao-li;SUN Wen-wen;QI Cong;LIU Qing-wu;BAO Shen-tao(Dermatological Department,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China;Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2021年第7期4405-4407,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家重点研发计划“中医药现代化研究”重点专项课题(No.2018YFC1705302)
国家自然科学基金青年科学基金项目(No.81804097)
北京市医院管理中心“青苗”计划(No.QML20181003)。
关键词
银屑病
血燥型
中医药
养血解毒汤
中药药浴
Psoriasis
Blood dryness syndrome
Traditional Chinese medicine
Yangxue Jiedu Decoction
Chinese medicine medicine bath
