摘要
目的研究一种过氧化氢银离子复方消毒剂对医疗器械的消毒与灭菌效果及其腐蚀性.方法采用载体浸泡杀菌试验和腐蚀性试验方法,对某过氧化氢银离子复方消毒剂杀菌效果及其腐蚀性进行观察.结果以浓度为65 g/L过氧化氢与84 mg/L银离子的复方消毒剂浸泡30 min,对载体上的枯草杆菌黑色变种芽孢杀灭对数值均>3.0,作用1 h无菌生长.在上述条件下,对污染于医疗器械的枯草杆菌黑色变种芽孢作用30 min、1 h,能分别达到消毒、灭菌合格要求,在反复取放浸泡医疗器械条件下,消毒作用1 h,可连续使用14 d达到消毒与灭菌要求.该消毒剂对不锈钢基本无腐蚀,对碳钢、铝、铜有不同程度腐蚀.结论该过氧化氢银离子复方消毒剂具有良好的杀灭细菌芽孢的效果,对不锈钢类医疗器械基本无腐蚀性.
Objective To study the disinfection and sterilization effect and corrosiveness of a compound disinfectant of hydrogen peroxide and silver ions on medical devices.Methods Carrier immersion bactericidal test and corrosiveness test were used to observe the disinfection effect and corrosiveness of a hydrogen peroxide and silver ions compound disinfectant.Results The compound disinfectant with a concentration of 65 g/L hydrogen peroxide and 84 mg/L silver ions was used to immerse the carrier for 30 min,and the logarithmic values of killing the spores of Bacillus subtilis var.niger were all>3.0,and the growth of bacteria cultures for 1 h was sterile.Under the abovementioned conditions,it could reach the qualification requirement of disinfection and sterilization respectively after 30 min and 1 h treatment of the spores of Bacillus subtilis var.niger on contaminated medical devices.Under the condition of taking out and immersing medical devices repeatedly,it could reach the requirements of disinfection and sterilization and could be used continuously for 14 days when it acted for 1 h.The disinfectant was basically noncorrosive to stainless steel,and had different degrees of corrosion to carbon steel,aluminum and copper.Conclusion The hydrogen peroxide and silver ions compound disinfectant has a good effect of killing bacterial spores and is basically noncorrosive to medical devices of stainless steel.
作者
刘南
沈田展鸿
王乙棋
朱兵
杨雪帆
LIU Nan;SHEN TIAN;Zhan-hong;WANG Yi-qi;ZHU Bing;YANG Xue-fan(Chongqing Municipal Center for Disease Control and Prevention,Chongqing 400042,China)
出处
《中国消毒学杂志》
CAS
2021年第7期481-483,487,共4页
Chinese Journal of Disinfection
基金
2018年重庆市技术创新与应用示范社会民生类一般项目(cstc2018jscx-msybX0177)。
关键词
过氧化氢
银离子
复方消毒剂
医疗器械
灭菌效果
腐蚀性
hydrogen peroxide
silver ion
compound disinfectant
medical devices
sterilization effect
corrosiveness
