摘要
目的调查甲状腺功能减退(简称甲减)患者合并抑郁的现状,并分析甲减患者抑郁发生的影响因素。方法本研究为横断面研究。采用便利抽样法,选取2018年3月—2020年3月在郑州大学第一附属医院就诊的110例甲减患者为研究对象,采用一般资料调查表、甲减健康知识评分、社会支持评定量表、汉密尔顿焦虑量表和汉密尔顿抑郁量表对患者进行调查,采用单因素分析和多因素Logistic回归分析甲减患者发生抑郁的影响因素。本研究共发放问卷110份,回收有效问卷110例,有效回收率为100%。结果110例甲减患者汉密尔顿抑郁量表评分为(12.54±2.97)分,有45例存在抑郁情况,占40.91%。45例存在抑郁的患者中,有21例同时存在焦虑情绪,占46.67%。抑郁患者与无抑郁患者的性别、术后甲减、甲减病情严重程度、药物替代治疗、围绝经期、经济收入、社会支持情况比较,差异均有统计学意义(P<0.05);多因素Logistic回归分析显示,性别、甲减病情严重程度、药物替代治疗、围绝经期、社会支持情况均是甲减患者发生抑郁的影响因素(P<0.05)。结论甲减患者抑郁发生率较高,性别、甲减病情严重程度、药物替代治疗、围绝经期、社会支持情况均是抑郁发生的影响因素。
Objective To explore the current status of hypothyroidism patients with depression,and analyze the influencing factors of depression in patients with hypothyroidism.Methods This study is a cross-sectional study.From March 2018 to March 2020,convenience sampling was used to select 110 patients with hypothyroidism in the First Affiliated Hospital of Zhengzhou University as the research object.The General Information Questionnaire,Hypothyroidism Health Knowledge Score,Social Support Rating Scale,Hamilton Anxiety Scale and Hamilton Depression Scale were used to investigate the patients.Single factor analysis and multivariate Logistic regression were used to analyze the influencing factors of depression in patients with hypothyroidism.A total of 110 questionnaires were distributed,and 110 valid questionnaires were returned,and the valid response rate was 100%.Results The Hamilton Depression Scale score of 110 patients with hypothyroidism was(12.54±2.97),and 45 cases had depression,accounting for 40.91%.Among the 45 patients with depression,21 patients also had anxiety,accounting for 46.67%.There were statistically significant differences in gender,postoperative hypothyroidism,severity of hypothyroidism,drug replacement therapy,perimenopausal period,economic income,and social support between depressed patients and non-depressed patients(P<0.05).Multivariate Logistic regression analysis showed that gender,severity of hypothyroidism,drug replacement therapy,perimenopausal period,and social support were influencing factors of depression in patients with hypothyroidism(P<0.05).Conclusions The incidence of depression in patients with hypothyroidism is relatively high.Gender,severity of hypothyroidism,drug replacement therapy,perimenopausal period,and social support are influencing factors for depression.
作者
岳建华
张向京
李晓丽
李建华
Yue Jianhua;Zhang Xiangjing;Li Xiaoli;Li Jianhua(Intervention Therapy Department,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China;Second Geriatrics Department,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China;Second Thyroid Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《中华现代护理杂志》
2021年第22期2958-2963,共6页
Chinese Journal of Modern Nursing
基金
河南省医学科技攻关计划项目(SB201902003)。
