摘要
目的:观察半夏厚朴汤联合雷贝拉唑治疗反流性食管炎的疗效及对患者生活质量的影响。方法:选取80例反流性食管炎患者,随机分为观察组与对照组,每组40例。对照组用雷贝拉唑治疗,观察组在对照组基础上联合半夏厚朴汤治疗,共2个月。比较2组治疗前后症状积分为主的反流性疾病问卷(RDQ)、食管内镜检查分级积分,同时采用美国波士顿健康研究所健康调查量表(SF-36)评价患者的生活质量,采用匹兹堡睡眠质量指数量表(PSQI)评价患者的睡眠质量。结果:与同组治疗前比较,治疗后2组RDQ积分、内镜检查分级积分及PSQI量表各项评分均降低(P<0.05),SF-36量表各维度评分均升高(P<0.05);与对照组治疗后比较,观察组治疗后RDQ积分、内镜检查分级积分及PSQI量表各项评分均较低(P<0.05),SF-36量表各维度评分均较高(P<0.05)。结论:半夏厚朴汤联合雷贝拉唑治疗反流性食管炎可有效促进食管黏膜炎症的恢复,改善患者的临床症状、生活质量及睡眠质量。
Objective:To observe the curative effect of Banxia Houpo tang combined with rabeprazole for reflux esophagiti and its effect on quality of life.Methods:A total of 80 cases of patients with reflux esophagiti were randomly divided into the observation group and the control group,40 cases in each group.The control group was treated with rabeprazole,and the observation group was additionally treated with Banxia Houpo tang based on the treatment of the control group.Both groups were treated for two months.Before and after treatment,the scores in Reflux Disease Questionnaire(RDQ)and grading of esophageal endoscopy were compared,the Short Form-36 Health Survey(SF-36)was applied to assess the quality of life of patients,and Pittsburgh Sleep Quality Index(PSQI)was used to evaluate the sleep quality.Results:After treatment,the scores of RDQ and grading of esophageal endoscopy as well as each score in PSQI in the two groups were decreased when compared with those before treatment(P<0.05),and each score in SF-36 was increased(P<0.05);the scores of RDQ and grading of esophageal endoscopy as well as each score in PSQI in the observation group were lower than those in the control group(P<0.05),and each score in SF-36 was higher(P<0.05).Conclusion:Banxia Houpo tang combined with rabeprazole for reflux esophagiti can effectively promote the recovery of esophageal mucosal inflammation,and improve the clinical symptoms,quality of life and sleep quality of patients.
作者
卞银燕
童晓群
徐燕芳
张鹰
BIAN Yinyan;TONG Xiaoqun;XU Yanfang;ZHANG Ying
出处
《新中医》
CAS
2021年第14期18-21,共4页
New Chinese Medicine
