摘要
目的探讨产褥感染的病原菌分布情况及妊娠结局。方法回顾性分析2010年1月至2020年12月在解放军总医院第一医学中心收治的产褥感染病例,统计微生物学特征、分娩方式、产程情况、妊娠结局等。结果2010年1月至2020年12月本院收治的孕产妇共22159例,产褥感染55例,外院转诊19例;患者平均最高体温为(39.36±0.76)℃,细菌感染导致血流感染率为41.8%(23/55),脓毒血症发生率为7.3%(4/55),脓毒性休克发生率为20.0%(11/55),切除子宫发生率为9.1%(5/55),死亡率为1.8%(1/55)。大肠埃希菌感染导致发生血流感染率为42.8%(12/28),脓毒血症发生率为7.1%(2/28),脓毒性休克发生率为14.3%(4/28),切除子宫发生率为7.1%(2/28)。活产33例中出现新生儿窒息9例,其中早期新生儿死亡1例,窒息患儿中7例因大肠埃希菌感染导致。结论感染仍是导致孕产妇死亡及严重并发症的重要原因之一,临床应给予高度重视。大肠埃希菌是导致孕产妇感染的主要菌种,可导致母儿严重不良结局。
Objective To investigate the distribution of pathogenic bacteria and pregnancy outcome of the puerperal infection.Methods The cases of the puerperal infection in the First Medical Center of Chinese PLA General Hospital were retrospectively analyzed from January 2010 to December 2020.Whose pathogenic bacteria,delivery mode,labor progress and pregnancy outcome of the patients were counted.Results There were 22,159 pregnant women in our hospital from January 2010 to December 2020,55 cases had puerperal infection,the infection rate was 0.25%.There were 19 cases of the 55 cases come from other hospitals.The maximum temperature was(39.36±0.76)℃.The bloodstream infectional rate was 41.8%(23/55),the sepsis rate was 7.3%(4/55),the rate of sepic shock was 20.0%(11/55),the rate of hysterectomy operation was 0.1%(5/55),the dead rate was 1.8%(1/55).The rate of the blood stream infection which the escherichia coli lead to was 41.8%(22/28),the sepsis rate was 7.1%(2/22),the rate of sepic shock was 14.3%(4/28),the rate of hysterectomy operation was 7.1%(2/28).9 cases had neonatal asphyxia and 1 case had early neonatal death of 33 cases live births,7 cases in children with asphyxia caused by Escherichia coli(E.coli)infection.Conclusions Infection is still one of the important causes lead to maternal death and serious complications,so we should be pay attention to that E.coliis the main bacterial strain which can lead to infection in pregnant,and it may result in serious adverse outcomes of mother and child.
作者
胡凌云
谢潇潇
李立安
徐亚君
王黎
周飞虎
郭旭
游艳琴
卢彦平
Hu Lingyun;Xie Xiaoxiao;Li Li'an;Xu Yajun;Wang Li;Zhou Feihu;Guo Xu;You Yanqin;Lu Yanping(Department of Obstetrics and Gynecology,the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China;Department of Critical Care Medicine,the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China;Department of Anesthesiology,the First Medical Center of Chinese PLA General Hospital,Beijing 100853,China)
出处
《发育医学电子杂志》
2021年第4期282-286,共5页
Journal of Developmental Medicine (Electronic Version)