摘要
目的:观察中药护骨胶囊治疗对骨质疏松性椎体压缩骨折患者生活质量的影响。方法:选取骨质疏松性椎体压缩骨折患者100例,分为治疗组50例和对照组50例,治疗组采用钙+维生素D+唑来磷酸静滴+护骨胶囊治疗,对照组采用钙+维生素D+唑来磷酸静滴治疗,治疗12个月后,使用国际骨质疏松基金会(International Osteoporosis Foundation,IOF)生活质量量表评分,分别从躯体疼痛、日常生活状态、家务劳动、日常活动、休闲及社交活动、一般健康观念、精神状况7个维度对患者生活质量进行测评,采用疼痛视觉模拟量表(Visual Analog Scale,VAS)对两组治疗12个月后疼痛症状进行对比。结果:两组数据采用独立样本资料检验,治疗组在疼痛、家务劳动、日常活动、休闲社交活动4个纬度评分均显著高于对照组(P<0.05);治疗组VAS评分优于对照组,差异有统计学意义(P<0.05)。结论:唑来膦酸+中药护骨胶囊治疗骨质疏松性胸腰椎骨折患者,生活质量高于单纯唑来膦酸的治疗,因此,护骨胶囊可以明显提高骨质疏松性胸腰椎骨折患者的生活质量。
Objective:To observe the effect of Hugu capsule(护骨胶囊)on the quality of life of patients with osteoporotic vertebral compression fracture.Methods:100 patients with osteoporotic vertebral compression fracture were divided into the treatment group(50 cases)and the control group(50 cases).The treatment group was treated with calcium+vitamin D+zoledronic acid intravenous drip+Hugu capsule.The control group was treated with calcium+vitamin D+zoledronic acid intravenous drip.After 12 months of treatment,IOF quality of life scale was used for scoring.The patients'quality of life was evaluated from 7 dimensions,namely,physical pain,daily life status,housework,daily activities,leisure and social activities,general health concepts,and mental status.Visual visual analogue scale(VAS)was used to compare the pain symptoms of the 2 groups after 12 months of treatment.Results:The scores of pain,housework,daily activities,leisure and social activities in the treatment group were significantly higher than those in the control group(P<0.05);VAS scores in the treatment group were better than those in the control group(P<0.05).Conclusion:The quality of life of patients with osteoporosis thoracolumbar fracture treated with zoledronic acid and Hugu capsule is higher than that treated with zoledronic acid alone.Therefore,Hugu capsule can significantly improve the quality of life of patients with osteoporosis thoracolumbar fracture.
作者
邵小武
黄雪芬
黄鑫
Shao Xiaowu;Huang Xuefen;Huang Xin
出处
《中医临床研究》
2021年第12期116-118,127,共4页
Clinical Journal Of Chinese Medicine
关键词
护骨胶囊
保守治疗
唑来膦酸
骨质疏松性胸腰椎骨折
生活质量
Hugu capsule
Conservative treatment
Zoledronic
Osteoporotic thoracolumbar fracture
Quality of life
