摘要
目的分析孕妇不同妊娠期开展甲状腺激素检验的效果。方法方便选取2019年1—12月在该院开展孕期检查的孕妇共148名为研究对象,包含48名早期妊娠孕妇、50名中期妊娠孕妇和50名晚期妊娠孕妇,另选取同期在该院开展检查的50名健康非孕期女性设为对照组,均开展甲状腺激素检测,对检测结果进行比较分析。结果早期、中期以及晚期妊娠组的FT3水平为(3.65±0.45)、(3.05±0.34)、(2.45±0.26)pmol/L,低于对照组(4.99±1.22)pmol/L,差异有统计学意义(F=125.27,P<0.05);早期、中期以及晚期妊娠组的FT4水平分别为(16.19±2.38)、(14.50±2.15)、(12.60±1.98)pmol/L低于对照组的(20.98±2.10)pmol/L,差异有统计学意义(F=138.63,P<0.05);早期、中期以及晚期妊娠组的TSH水平分别为(8.15±0.36)、(12.70±0.30)、(15.32±0.38)mIU/L高于对照组(2.06±0.45)mIU/L,差异有统计学意义(F=11898.41,P<0.05);伴随孕周增加,FT3及FT4水平不断降低,TSH水平不断升高。早期、中期以及晚期妊娠组的甲状腺病患病率分别为20.83%、18.00%、16.00%,高于对照组(2.00%),差异有统计学意义(χ^(2)=8.596,P<0.05)。早期以及中期妊娠组的TPOAb及A-TG阳性率高于对照组,差异有统计学意义(P<0.05),且伴随孕周增长,TPOAb以及A-TG阳性率不断下降。结论孕妇不同妊娠期甲状腺激素含量存在较大差异,需加强孕期检查,对碘摄入量进行及时调整,达到优生优育。
Objective To analyze the effect of thyroid hormone tests on pregnant women during different pregnancy periods.Methods A total of 148 pregnant women undergoing pregnancy examinations in the hospital from January to December 2019 were conveniently selected as the research objects,including 48 pregnant women in early pregnancy,50 pregnant women in the second trimester,and 50 pregnant women in late pregnancy.Another 50 cases were selected in the hospital during the same period.Healthy non-pregnant women were set as the control group,and thyroid hormone testing was carried out,and the testing results were compared and analyzed.Results The levels of FT3 in the early,middle and late pregnancy groups were(3.65±0.45)pmol/L,(3.05±0.34)pmol/L,(2.45±0.26)pmol/L,which was lower than the control group(4.99±1.22)pmol/L,the difference was statistically significant(F=125.27,P<0.05);FT4 levels in the early,middle and late pregnancy groups were(16.19±2.38)pmol/L,(14.50±2.15)pmol/L,and(12.60±1.98)pmol/L lower than the control group(20.98±2.10)pmol/L,the difference was statistically significant(F=138.63,P<0.05);the TSH levels of the early,middle and late pregnancy groups were(8.15±0.36)mIU/L,(12.70±0.30)mIU/L,(15.32±0.38)mIU/L were higher than the control group(2.06±0.45)mIU/L,the difference was statistically significant(F=11898.41,P<0.05);with the increase in gestational age,the levels of FT3 and FT4 kept decreasing,TSH level continued to rise.The prevalence of thyroid disease in the early,middle and late pregnancy groups was 20.83%,18.00%,and 16.00%,respectively,which was higher than that of the control group(2.00%),the difference was statistically significant(χ^(2)=8.596,P<0.05).The positive rates of TPOAb and A-TG in the early and mid-pregnancy groups were higher than those in the control group,the difference was statistically significant(P<0.05),and the positive rates of TPOAb and A-TG continued to decrease with the increase in gestational age.Conclusion There is a big difference in the thyroid hormone content of pregnant women in different pregnancy periods.It is necessary to strengthen the pregnancy examination and adjust the iodine intake in time to achieve good birth and good childbirth.
作者
吴华美
李建宁
陈伟军
WU Huamei;LI Jianning;CHEN Weijun(Department of Laboratory Medicine,Leizhou People's Hospital of Guangdong Province,Leizhou,Guangdong Province,524200 China)
出处
《中外医疗》
2021年第18期179-181,共3页
China & Foreign Medical Treatment
关键词
甲状腺激素
孕妇
晚期妊娠
中期妊娠
早期妊娠
检验
Thyroid hormone
Pregnant women
Late pregnancy
Mid-term pregnancy
Early pregnancy
Test
