摘要
挥发油广泛分布于中药材中,化学成分复杂,主要成分有萜烯类、芳香族、脂肪族和含氮硫类四大类,具有抑菌抗炎、镇痛抗肿瘤、抗氧化、抗衰老等多种药理活性。其在医疗保健、农业增效、日用产品等方面均有广泛应用。近年来有中药精油止痛相关的大量研究,但缺乏系统性归纳,笔者通过查阅近几年中外文文献,发现中药精油发挥止痛功效的机制主要有调节中枢神经系统、抗炎镇痛及解痉止痛等,但确切的机制有待进一步考证。该文从疼痛的分类、产生、止痛机制以及联合其他技术等方面对中药精油止痛研究进展进行综述,以期为日后相关研究提供参考。
Volatile oil is widely distributed in Chinese medicinal materials with complex chemical components. The main components are terpenes,aromatics,aliphatics,and nitrogen and sulfur containing. It has a variety of pharmacological activities. Such as antibacterial,anti-inflammatory,analgesic,anti-tumor,antioxidant,anti-aging and so on. It is widely used in medical and health care,agricultural efficiency enhancement,and daily products. In recent years,there have been a large number of studies on the pain relief of traditional Chinese medicine(TCM) essential oils,but there is no systematic generalization. The author found that the mechanism of TCM essential oils to exert analgesic effects mainly includes regulation of the central nervous system,anti-inflammatory and analgesic,antispasmodic and analgesic effects by consulting Chinese and foreign literatures in recent years,but the exact mechanism needs to be further verified. This article reviews the research progress of TCM essential oil pain relief from the aspects of pain classification, generation, analgesic mechanism and combination of other technologies,in order to provide reference for related research in the future.
作者
许攀
沈倩
杨明
臧振中
陈丽梅
朱卫丰
陈丽华
刘丽丽
管咏梅
XU Pan;SHEN Qian;YANG Ming;ZANG Zhen-zhong;CHEN Li-mei;ZHU Wei-feng;CHEN Li-hua;LIU Li-li;GUAN Yong-mei(Key Laboratory of Modern Chinese Medicine Preparation of Ministry of Education,Jiangxi University of Chinese Medicine,Nanchang 330004,China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2021年第17期211-216,共6页
Chinese Journal of Experimental Traditional Medical Formulae
基金
江西省重大科研研发专项(20194ABC28009)
江西省2020年大学生创新创业训练计划项目(S202010412051)
2020年度江西省教育厅科学技术研究项目(GJJ201251)。
关键词
中药精油
止痛
芳香疗法
疼痛类型
止痛机制
essential oils of traditional Chinese medicine
analgesia
aromatherapy
types of pain
analgesic mechanism
