摘要
目的分析新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)疫情对卒中住院患者认知功能和心理状态的影响。方法本研究回顾性纳入2020年1月1日-4月30日COVID-19疫情期间于首都医科大学附属北京天坛医院神经内科住院的卒中患者作为观察组,以2019年1月1日-4月30日同科室住院的卒中患者为对照组。比较两组患者住院期间MoCA和9项患者健康问卷(patient health questionnare-9,PHQ-9)抑郁症筛查量表评分的差异;比较两组患者3个月随访时的抑郁症筛查量表-2项患者健康问卷(Patient Health Questionnare-2,PHQ-2)评分的差异。结果本研究共纳入观察组患者106例,对照组患者180例。观察组患者既往心房颤动病史比例较高(13.21%vs 4.44%,P=0.01)、既往心肌梗死病史比例较低(0 vs 5.56%,P=0.01)。住院期间,两组患者MoCA评分差异无统计学意义,观察组PHQ-9抑郁症筛查量表得分[13(11~16)vs 7(4~11),P<0.01]显著高于对照组。以PHQ-9评分≥10分作为诊断抑郁情绪的界值,观察组出现卒中后抑郁情绪的比例高于对照组(39.62%vs 35.00%,P<0.01)。3个月随访时,观察组PHQ-2评分高于对照组[4(3~5)vs 3(2~4),P<0.01]。结论COVID-19疫情时期卒中住院患者更易出现抑郁情绪,应给予相应的心理干预,以改善患者心理健康状况。
Objective To analyze the influence of coronavirus disease 2019(COVID-19)on cognitive function and psychological state of stroke inpatients.Methods In this retrospective study,inpatients with stroke admitted to Department of Neurology of Beijing Tiantan Hospital,Capital Medical University during COVID-19 pandemic from January 1 to April 30,2020 were included as the observation group,and inpatients with stroke in the same department from January 1 to April 30,2019 were included as the control group.MoCA and the 9-item patient health questionnaire(PHQ-9)scale to screen depression were used in the patients of both groups.The 2-item patient health questionnaire(PHQ-2)was used in all the included patients to screen depression at 3-month follow up.Results A total of 106 patients in observation group and 180 in control group were included in this study.Compared to control group,the proportion of patients with a history of atrial fibrillation in observation group was higher(13.21%vs 4.44%,P=0.01)and the proportion of patients with a history of myocardial infarction was lower (0 vs 5.56%, P =0.01). There was no statistical differencein MoCA score between the two groups, but PHQ-9 score of the observation group [13 (11-16) vs 7(4-11), P <0.01] was higher. With PHQ-9 score ≥10 points as a criterion for diagnosing depression,the proportion of post-stroke depression patients in observation group was higher than that incontrol group (39.62% vs 35.00%, P <0.01). At 3-month follow-up, PHQ-2 score in observationgroup was also higher than that in control group [4 (3-5) vs 3 (2-5), P <0.01].Conclusions Inpatients with stroke were more prone to become depressed during the COVID-19epidemic, and appropriate psychological interventions should be given to improve the patients’mental health.
作者
龚浠平
李轶
柴明东
余苹
赵性泉
王拥军
董可辉
GONG Xi-Ping;LI Yi;CHAI Ming-Dong;YU Ping;ZHAO Xing-Quan;WANG Yong-Jun;DONG Ke-Hui(Department of Neurology,Beijing Tiantan Hospital,Capital Medical University,China National Clinical Research Center for Neurological Diseases,Beijing 100070,China;Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)
出处
《中国卒中杂志》
2021年第8期834-838,共5页
Chinese Journal of Stroke
基金
科技部国家重点研发计划(2020YFC2005304)
北京市临床重点专科项目。
关键词
新型冠状病毒肺炎
卒中
认知功能
抑郁
Coronavirus disease 2019
Stroke
Cognitive function
Depression
