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个性化3D打印多孔钽植入假体设计的基本原则 被引量:3

Basic principles for designing 3D-printed personalized porous tantalum prosthesis
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摘要 目的总结个性化多孔钽假体设计的基本原则,以指导假体模型设计,减少设计风险,满足临床应用要求。方法从53例三维(3D)打印多孔钽植入假体的设计中,综合考虑假体(尺寸、力学性能)、骨组织(生物力学、力生物学特征)及钽材(密度、价格)的影响,总结多孔钽植入假体设计的基本原则。结果个性化3D打印多孔钽假体的设计需要满足“四性原则”,即假体解剖匹配性原则、假体安全性原则、骨组织受力有效性原则、骨组织安全性原则;并在满足“四性原则”的基础上进一步考虑假体成本最低化原则。按“四性原则”设计的多孔钽植入假体,经临床应用和随访(最长随访时间3年)发现,患者缺损部位功能恢复良好,无1例失败。结论“四性原则”可保障个性化多钽假体在临床应用上的有效性和安全性,结合成本最低化原则,则可进一步促进个性化多孔钽的临床应用。 Objective To summarize the basic principles for designing the personalized porous tantalum prostheses in order to guide the model design of prostheses,reduce the design risks and satisfy the clinical requirements.Methods In the design of 53 cases of 3D-printed porous tantalum prostheses,the influences of prostheses(size,mechanical properties),bone tissue(biomechanical and mechanobiological features)and tantalum material(density and cost)were comprehensively considered,thereby the basic principles for designing porous tantalum prostheses were summarized.Results The design of personalized 3D-printed porous tantalum prostheses needed to satisfy"four basic principles",including the anatomical matching principle of prostheses,safety principle of prostheses,effectiveness principle of stress in bone tissue,and safety principle of bone tissue.On the basis of satisfying"four basic principles",the cost minimization principle was further considered.For the porous tantalum prostheses designed according to"four basic principles",the clinical application and follow-up(the longest follow-up period 3 years)found that the function in the defect site of the patients received the designed porous tantalum prostheses was recovered well with no failure case.Conclusion The four basic principles can guarantee the effectiveness and safety of the personalized porous tantalum prostheses in clinical application.When combining with the cost minimization principle,the clinical application of personalized tantalum prostheses can be further facilitated.
作者 刘洋 吴先哲 马幸双 何鹏 王富友 罗彦凤 LIU Yang;WU Xianzhe;MA Xingshuang;HE Peng;WANG Fuyou;LUO Yanfeng(College of Bioengineering,Chongqing University/Ministry of Education Key Laboratory of Biorheological Science and Technology,Chongqing 400030,China;Chongqing Institute of Optics and Mechanics,Chongqing 401123,China;Department of Joint Surgery,First Affiliated Hospital of Army Military Medical University,Chongqing 400038,China)
出处 《重庆医学》 CAS 2021年第16期2822-2825,2830,共5页 Chongqing medicine
基金 “十三五”国家重点研发计划课题(2016YFB1101401)。
关键词 三维打印技术 假体 多孔钽 骨缺损 个性化 基本原则 3D printing technology prosthesis porous tantalum bone defect personalization fundamental principles
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