摘要
目的探讨肠内营养干预对肌少症患者骨代谢及生活质量改善的应用价值。方法选取2019年6月至2020年10月杭州市第三人民医院老年科收治的肌少症患者60例,在日常饮食基础上每天额外增服整蛋白型肠内营养剂进行肠内营养干预。比较分析患者干预前后的体重、四肢骨骼肌质量指数(appendicular skeletal muscle mass index,ASMI)、步速、握力、日常生活活动能力量表(activity of daily living,ADL)评分、疼痛数字评价量表(numerical rating scale,NRS)评分、骨密度T值、维生素D和血钙水平。结果与干预前比较,肠内营养干预2个月后患者的体重、步速、握力、骨密度T值均显著升高(P<0.05),NRS评分显著下降(P<0.05);肠内营养干预3个月后患者的体重、ASMI、步速、握力、ADL评分、骨密度T值、维生素D和血钙水平均显著升高(P<0.05),NRS评分显著下降(P<0.05)。与肠内营养干预2个月时比较,肠内营养干预3个月后患者的体重、ASMI、ADL评分、骨密度T值、维生素D和血钙水平均显著升高(P<0.05),NRS评分显著下降(P<0.05)。结论肠内营养干预可以改善肌少症患者的骨代谢,增加患者的骨骼密度,缓解疼痛症状,提高运动能力,显著改善患者的生活质量。
Objective To explore the application value of enteral nutrition intervention on the improvement of bone metabolism and quality of life in patients with sarcopenia.Method From June 2019 to October 2020,60 sarcopenia patients admitted to the department of geriatrics in Hangzhou Third People’s Hospital were selected,and additional intacted protein enteral nutrition powder was taken daily on the basis of daily diet for enteral nutrition intervention.Compared and analyzed the patient’s weight,appendicular skeletal muscle mass index(ASMI),gait speed,grip strength,activity of daily living scales(ADL),numerical rating scale(NRS),T value of bone mineral density,vitamin D,blood calcium level before and after intervention.Result After 2 months of nutritional intervention,the patient’s body weight,gait speed,grip strength,and T value of bone mineral density were significantly higher than those before the intervention(P<0.05),and the NRS was significantly lower than that before the intervention(P<0.05).After 3 months of intervention,the patient’s body weight,ASMI,gait speed,grip strength,ADL,T value of bone mineral density,vitamin D and blood calcium levels were significantly higher than those before the intervention(P<0.05),and the NRS was significantly lower than that before the intervention(P<0.05).After 3 months of intervention,weight,ASMI,ADL,T value of bone mineral density,vitamin D,blood calcium increased significantly compared with the intervention for 2 months(P<0.05),NRS decreased significantly compared with the intervention for 2 months(P<0.05).Conclusion Enteral nutrition intervention can improve the bone metabolism of patients with sarcopenia,and increase their bone density,relieve pain symptoms,and improve exercise capacity,which has important clinical significance for improving the quality of life of patients.
作者
高康璐
马璐瑶
王琴
林萍
Gao Kanglu;Ma Luyao;Wang Qin;Lin Ping(Department of Gerontology,Hangzhou Third People’s Hospital,Zhejiang Hangzhou 310009,China)
出处
《中国医刊》
CAS
2021年第9期999-1002,共4页
Chinese Journal of Medicine
基金
浙江省医药卫生科技计划面上项目(2018KY593,2019KY502)
浙江省杭州市卫生计生科技计划重点项目(2018Z05)。
关键词
肠内营养
整蛋白型肠内营养剂
肌少症
骨代谢
生活质量
Enteral nutrition
Intacted protein enteral nutrition powder
Sarcopenia
Bone metabolism
Quality of life
