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干扰素α2b雾化在呼吸道合胞病毒肺炎患儿治疗中的临床价值分析 被引量:1

Clinical value of interferon α2b atomization in the treatment of children with respiratory syncytial virus pneumonia
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摘要 目的分析干扰素α2b雾化在呼吸道合胞病毒肺炎患儿治疗中的临床价值.方法选取80例本院就诊的呼吸道合胞病毒肺炎患儿,所有患儿随机均分到对照组(盐酸氨溴索口服液)、研究组(盐酸氨溴索口服液联合干扰素α2b).记录分析患者用药疗效、肺功能状况以及炎症因子状况.结果研究组症状消失时间、病毒转阴时间以及住院时间明显比对照组短(P<0.05).研究组用药后PEF、FEV1、FVC均明显比对照组大(P<0.05).研究组用药后各炎症因子含量水平均优于对照组(P<0.05).结论雾化吸入干扰素α2b能够在用药后更短时间内给予患儿有效治疗,提高预后肺功能,降低患儿炎症反应. Objective To analyze the rliniral value of interferon 2B atomization in the treatment of children with respiratory syncytial virus pneumonia.Methods 80 children with respiratory syncytial virus pneumonia in our hospital from March 2019 to March 2020 were randomly divided into control group(amhroxol hydroc hloride oral liquid)and study group(amhroxol hydrochloride oral liquid combined with interferon α2b).The efficacy,pulmonary function and inflammatory factors were recorded and analyzed.Results The symptom disappearance lime,virus negative time and hospitalization lime of the study group were significantly shorter than those of the control group(P<0.05).FEF,FEV,and FVC in the study group were signifirantly higher than those in the control group(P<0.05).The levels of inflammatory factors in the study group were better than those in the control group (P<0.05).Conclusion Aerosol inhalation of interferon α2b can give children effective treatment in a shorter time after medication,improve the prognosis of lung function and reduce the inflammatory reaction.
作者 陈丽容 余洽超 Chen Lirong;Yu Qiachao(Kaiping Central Hospital pediatrics Kaiping,Guangdong,529300)
出处 《首都食品与医药》 2021年第16期59-60,共2页 Capital Food Medicine
关键词 呼吸道合胞病毒肺炎 患儿 干扰素Α2B 雾化 临床价值 respiratory syncytial virus pneumonia Children Interferonα2b Atomization Clinical value
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