摘要
粘细菌(Myxobacteria)是一类具有复杂多细胞行为、能够广泛捕食各类细菌和真菌并能产生丰富次级代谢产物的药源微生物,具有重要研究和应用价值。然而,由于资源挖掘困难,多相分类研究进展缓慢,严重阻碍了粘细菌的开发利用。本文对粘细菌的特性、分离和纯化方法、目前存在的不足及改进措施进行阐述,并对粘细菌多相分类研究进展及存在的问题进行解析。另外,结合当前技术手段和发展现状,进一步对粘细菌的未来发展趋势进行展望,以期为相关研究提供参考。
Myxobacteria are a kind of medical microorganisms that could produce abundant secondary metabolites,show complex multicellular behaviors and prey kinds of bacteria and fungi.Therefore,myxobacteria have important values of research and application.However,it seriously impedes myxobacterial mining and utilization because of their difficulties to isolate,cultivate,and research in polyphase classification.This review described myxobacterial features,methods for isolation and purification,and discussed existing problems and improvement measures.In addition,we also analyzed the research status in polyphase classification of myxobacteria.Based on the current technical means and research progress,the future research trends of myxobacteria were prospected.This review aims to provide help to relevant researches on myxobacteria in the future.
作者
王春玲
吕颖颖
姚青
李安章
朱红惠
WANG Chunling;Yingying LÜ;YAO Qing;LI Anzhang;ZHU Honghui(Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application,State Key Laboratory of Applied Microbiology Southern China,Guangdong Institute of Microbiology,Guangdong Academy of Sciences,Guangzhou,Guangdong 510070,China;Guangdong Provincial Key Laboratory of Microbial Signals and Disease Control,College of Horticulture,South China Agricultural University,Guangzhou,Guangdong 510642,China)
出处
《微生物学通报》
CAS
CSCD
北大核心
2021年第8期2870-2880,共11页
Microbiology China
基金
国家自然科学基金(31800003)
广东省科学院建设国内一流研究机构行动专项资金(2020GDASYL-20200103032)
广东省科技计划(2019B030316010)。
关键词
粘细菌
资源挖掘
多相分类研究
myxobacteria
resource mining
polyphase classification
