摘要
目的:研究气血两虚型产后风湿的兼夹证分布规律,评估益气养血方治疗气血两虚型产后风湿的疗效。方法:纳入气血两虚型产后风湿患者60例,统计兼夹证出现频次。以益气养血方随证加减治疗8周,通过比较治疗前后中医证候积分、视觉模拟评分法(VAS)评分、抑郁自评量表(SDS)评分、世界卫生组织生存质量测定量表简表(WHOQOL-BREF)评分进行疗效和安全性评价。并对不同兼证的气血两虚型产后风湿患者治疗后的疗效进行对比分析。结果:入组气血两虚型产后风湿患者兼夹证出现频次如下:表虚不固(48.21%)、肝肾亏虚(39.29%)、肝郁气滞(21.25%)、脾虚夹湿(19.64%)、瘀血阻滞(3.75%)。治疗后中医证候积分、VAS评分、SDS评分、WHOQOL-BREF评分均较治疗前改善,差异有统计学意义(P<0.01);益气养血方治疗产后风湿总有效率为94.64%;不同的兼夹证治疗疗效不同,表虚不固、脾虚夹湿、肝肾亏虚、肝郁气滞的显效率分别为58.82%、28.57%、21.43%、12.50%,差异具有统计学意义(P<0.05)。结论:益气养血方治疗气血两虚型产后风湿临床疗效确切,并且不同兼夹证占比及其临床疗效存在明显差异,表虚不固证临床疗效最好,该研究为产后风湿的中医治疗提供了有益的参考依据。
Objective:To study the distribution rules of accompanying syndromes of qi and blood deficiency type postpartum rheumatism,and to evaluate the therapeutic effect of Yiqi Yangxue Formula(益气养血方)on postpartum rheumatism of qi and blood deficiency type.Methods:A total of 60 cases of postpartum rheumatism patients with deficiency of qi and blood were recruited and statistics of the frequency of different accompanying syndromes was surveyed.The patients were treated with modified Yiqi Yangxue Formula for 8 weeks.The clinic efficacy and safety evaluation were conducted by the score of traditional Chinese medicine(TCM)syndrome,Visual Analogue scale(VAS),Self-rating depression scale(SDS)and the brief scale of quality of life of WHO(WHOQOL-BREF).Results:The occurrence frequency of different accompanying symptoms followed the order of lung qi deficiency(48.21%)>liver and kidney deficiency(39.29%)>liver qi stagnation(21.25%)>spleen deficiency with dampness(19.64%)>blood stasis(3.75%).The improved scores of TCM syndrome,VAS,SDS and WHOQOL-BREF were of statistical significance(P<0.01).The total effective rate of Yiqi Yangxue Formula on postpartum rheumatism of qi and blood deficiency type was up to 94.64%.In addition,the significant effective rate was of significant difference in different accompanying symptoms(P<0.05),which was 58.82%,28.57%,21.43%and 12.50%respectively in the lung qi deficiency,the spleen deficiency with dampness,liver and kidney deficiency and liver qi stagnation.Conclusions:The clinical effect of Yiqi Yangxue Formula on postpartum rheumatism of qi and blood deficiency is accurate,and there are obvious differences between proportion of different syndromes and their clinical effects.The clinical effect of Yiqi Yangxue Formula on the syndrome of lung qi deficiency is the best.These rules provide useful reference for the TCM diagnosis and treatment of postpartum rheumatism.
作者
张莹
李雪微
吴斌
李延萍
ZHANG Ying;LI Xuewei;WU Bin;LI Yanping(Department of Rheumatism,Chongqing Traditional Chinese Medicine Hospital,Chongqing 400021,China)
出处
《山东中医杂志》
2021年第9期943-947,共5页
Shandong Journal of Traditional Chinese Medicine
基金
重庆市中医院李延萍名中医工作室建设项目(编号:cqzyymzygzs-001)
重庆市科研机构绩效激励引导专项(编号:cstc2019jxjl1130011)。
关键词
产后风湿
气血两虚
表虚不固
肝肾亏虚
肝郁气滞
脾虚夹湿
瘀血阻滞
益气养血方
postpartum rheumatism
deficiency of qi and blood
order of lung qi deficiency
liver and kidney deficiency
liver qi stagnation
spleen deficiency with dampness
blood stasis
Yiqi Yangxue Formula
