摘要
目的分析球后神经阻滞联合全身麻醉在角膜移植术中的应用效果。方法研究讨论了56例角膜移植术患者的麻醉情况,患者在2017年6月—2020年4月期间入院,按照时间顺序将患者分成两组,一组使用全麻,一组使用球后神经阻滞联合全身麻醉方案,分别作为对照组和观察组,比较两组临床指标波动情况、麻醉药物用量和不良反应。结果观察组血压波动值(7.23±2.11)mmHg,心率波动值(7.26±3.26)次/min,数据低于对照组,差异有统计学意义(t=9.997、7.048,P<0.05);观察组术中瑞芬太尼用量是(1.12±0.37)mg,丙泊酚用量是(273.34±47.28)mg,比对照组更低,差异有统计学意义(t=11.335、5.388,P<0.05);观察组与对照组术后不良反应发生率分别是7.14%、10.71%,差异无统计学意义(χ^(2)=0.000,P>0.05);观察组IL-1(53.34±6.35)pg/mL,IL-6(23.83±4.55)pg/mL,TNF-α(17.34±4.27)pg/mL低于对照组,差异有统计学意义(t=10.687、12.080、5.366,P<0.05)。结论球后神经阻滞联合全身麻醉在角膜移植术中的应用可以减少麻醉用药,并达到良好的麻醉效果,减少术中体征波动,维持体征平稳,术后不良反应少,安全可靠。
Objective To analyze the effect of retrobulbar nerve block combined with general anesthesia in keratoplasty.Methods The study discussed the anesthesia of 56 patients undergoing keratoplasty.The patients were admitted to the hospital from June 2017 to April 2020.The patients were divided into two groups in chronological order,one group using general anesthesia and the other using posterior nerve block combined with general anesthesia was used as the control group and the observation group to compare the fluctuation of clinical indicators,the dosage of anesthetics and adverse reactions between the two groups.Results The blood pressure fluctuation value of the observation group was(7.23±2.11)mmHg,and the heart rate fluctuation value(7.26±3.26)times/min.The data was lower than that of the control group,the difference was statistically significant(t=9.997,7.048,P<0.05);the observation group was remifentanil during operation(1.12±0.37)mg,and the dosage of propofol was(273.34±47.28)mg,which was lower than the control group,the difference was statistically significant(t=11.335,5.388,P<0.05);the incidence of adverse reactions in the observation group and the control group were respectively 7.14%,10.71%,the difference between the groups was not statistically significant(χ^(2)=0.000,P>0.05);the observation group IL-1 was(53.34±6.35)pg/mL,IL-6 was(23.83±4.55)pg/mL,TNF-αwas(17.34±4.27)pg/mL,the data was lower than the control group,the difference was statistically significant(t=10.687,12.080,5.366,P<0.05).Conclusion The application of retrobulbar nerve block combined with general anesthesia in keratoplasty can reduce the use of anesthesia,and achieve good anesthesia effects,reduce intraoperative sign fluctuations,maintain stable signs,and have fewer postoperative adverse reactions,which is safe and reliable.
作者
李佳林
张莉莎
邴彦秋
LI Jialin;ZHANG Lisha;BING Yanqiu(Department of Anesthesiology,Beijing Aier Yingzhi Eye Hospital Co.,Ltd.,Beijing,100020 China;Department of Anesthesiology,Shenyang Aier Optometry Hospital,Shenyang,Liaoning Province,111000 China)
出处
《世界复合医学》
2021年第6期32-34,38,共4页
World Journal of Complex Medicine
关键词
球后神经阻滞
全身麻醉
角膜移植术
应用效果
体征波动
麻醉药用量
不良反应
Retrobulbar nerve block
General anesthesia
Keratoplasty
Application effect
Physical signs fluctuations
Anesthetic dosage
Adverse reactions
