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真实世界下异病同治理论治疗恶性肿瘤的临床证型及用药特点分析 被引量:2

Clinical syndrome and drug characteristics oftheory of same treatment for different diseases on malignant tumor in real medical records
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摘要 目的基于真实病历,在异病同治理论指导下,对3797例恶性肿瘤的临床证型及用药特点进行分析。方法采集河南中医药大学第二附属医院肿瘤科服用中药的恶性肿瘤患者3797例,通过建立数据库,对患者的临床证型及用药特点进行分析,整理出扶正固本法的临证思路和用药特点。结果3797例恶性肿瘤患者,以肺癌、肠癌、胃癌为多;中医证型以肺脾气虚、气滞痰凝、气血亏虚、痰瘀互结证为多;中药方剂以厚朴温中汤、参苓白术散、当归补血汤、二陈汤、半夏泻心汤、生脉饮为主;中药以茯苓、党参、炒白术、黄芪等为主。结论异病同治理论在中医恶性肿瘤治疗中具有指导意义,脾肾阳虚、痰瘀互结是晚期恶性肿瘤的重要病机,温肾健脾、化痰散瘀法是治疗恶性肿瘤的重要治法。 Objective To analyze the clinical syndrome and drug characteristics of theory of same treatmentfor different disease on 3797 patients with malignant tumor(MT) based on real medical records.Methods Totally 3797 MTpatients,who taking Chinese medicine at Department of Oncology,The Second Affiliated Hospital of Henan University of Chinese Medicine,were enrolled.A databaseestablishmentwere used to analyze clinical syndrome and drug characteristics,aim to sort out the Clinical thinking and drug characteristics of Fuzheng Guben method.Results Among 3797 MT,lung cancer,bowel cancer,gastric cancerwere most common types of tumors;lung spleen-deficiency,Qi stagnation and phlegm coagulation,qi-blood deficiency,phlegm-blood stasis were most common types of Traditional Chinese Medicine(TCM) syndrome;Hopu Wenzhong Soup,Shenling Baishu San,Erchen Decoction,Danggui Buxue Decoction,Banxia Xiexin Decoction,pulse-activating were commonly used TCM prescription;Fuling,Dangshen,Fried baishu,Huangqi were commonly used Chinese Medicine.Conclusion Theory of same treatment for different diseaseshas guiding significance for MT in TCM.Spleen-kidney yang deficiency and phlegm-blood stasis are important pathogenesis of advanced MT,warming kidney and invigorating spleen and phlegm-transforming stasis-dissipating therapy are important treatment methods.
作者 李洪霖 邵帅 陈梦利 郗昱檀 常思思 董良 马纯政 LI Honglin;SHAO Shuai;CHEN Mengli;XI YuTan;CHANG Sisi;DONG Liang;MA Chunzheng(Department of Oncology,The Second Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou,Henan450002;不详)
出处 《河北中医》 2021年第4期571-574,共4页 Hebei Journal of Traditional Chinese Medicine
基金 国家自然科学基金委员会资助项目(编号:81804057) 河南省中医管理局国家中医临床研究基地科研专项课题(编号:2017djzx016) 河南省卫生健康委员会中医药科学研究专项课题(编号:2019JDZX031)。
关键词 肿瘤 异病同治 扶正固本 化痰散结 Tumor Different disease with same treatment Fuzheng Guben method Improve the blood stasis and phlegm turbidity
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