摘要
目的:对某医院非麻醉性镇痛药的临床应用情况进行分析,为医疗机构非麻醉性镇痛药的规范化管理和临床合理用药提供参考和依据。方法:采用回顾性分析方法,从某医院信息HIS系统中调取2020年1月至2020年12月使用量和使用金额排名前4的非麻醉性镇痛药,包括地佐辛、布托啡诺、帕瑞昔布和布洛芬,收集包括病区、病人年龄、诊断、药品名称、规格、剂型等基本信息,对适应证、药品选择、用法用量、用药天数、联合用药等方面的合理性进行统计分析。结果:在适应证和药品选择方面的合理率是100%,在用法用量、用药天数和联合用药方面,均存在不合理用药现象。主要表现在布托啡诺用量过大,布洛芬分别和艾瑞昔布、帕瑞昔布、塞来昔布联合用药不合理,帕瑞昔布用药天数偏长,酒石酸布托啡诺和阿片类药品联合使用缺乏循证证据。结论:加强监管非麻醉性镇痛药的临床应用,规范这些药品的用法用量、用药天数和联合用药。
Objective:The clinical application of non-narcotic analgesics in a hospital was analyzed to provide reference and basis for the standardized management and rational clinical use of non-narcotic analgesics in medical institutions.Methods:Retrospective analysis was conducted to select the top 4 non-narcotic analgesics,including desoxine,butorphanol,parecoxib and ibuprofen,from the information system HIS of a hospital from January 2020 to December 2020,and to collect basic information including the patient area,patient age,diagnosis,drug name,specification,dosage form and so on.The rationality of indication,drug selection,usage and dosage,days of drug use and combination of drug use were statistically analyzed.Results:The rational rate of indication and drug selection was 100%.Irrational drug use existed in usage and dosage,duration of drug use and combination of drug use.The main manifestations were excessive dosage of butorphanol,unreasonable combination of ibuprofen and erecoxib,parecoxib and celecoxib,long days of parecoxib medication,and lack of evidences for the combined use of butorphanol tartrate and opioids.Conclusion:The clinical application of non-narcotic analgesics should be supervised,and the usage,dosage,duration and combination of these drugs should be regulated.
作者
孙晓春
蔡军
SUN Xiaochun;CAI Jun(The First Affiliated Hospital of Nanchang University,Nanchang Jiangxi 330006,China)
出处
《药品评价》
CAS
2021年第14期852-854,共3页
Drug Evaluation
基金
北京康盟慈善基金会医学科研发展基金项目(TB208017)
江西省卫生健康委科技计划(20165178)。
