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中医药联合腹腔热灌注治疗结直肠癌的研究进展 被引量:2

Research Progress of Traditional Chinese Medicine Combined with Intraperitoneal Hyperthermia in the Treatment of Colorectal Cancer
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摘要 结直肠癌属于消化道常见恶性肿瘤疾病,有着较高的复发率、转移率、病死率,对患者生命健康有着较大威胁,故而受到国内外研究者的高度重视。临床治疗该疾病的方法一般为手术、化疗、放疗等,但放化疗法对机体的损伤较大,多数患者不耐受。中医药可以从多角度、多途径、个性化地进行综合干预,有利于调节机体状态,提高免疫力,辅助提高治疗效果。腹腔热灌注疗法近些年来被广泛应用于胃癌、卵巢癌等恶性肿瘤当中,是一种加热化疗药物到43℃左右后灌注到腹腔内的方式,且在灌注液中加入中药,通过高温促使药物的渗透力增强,有效杀灭脱落癌细胞,防止癌细胞转移或者将其灭活的技术,有利于提高治疗效果。笔者查阅诸多研究,对中医药联合腹腔热灌注治疗结直肠癌的可行性展开综述。 Colorectal cancer is a common malignant tumor disease of the digestive tract.It has a high recurrence rate,metastasis rate,and mortality rate.It poses a greater threat to the life and health of patients,so it is highly valued by researchers at home and abroad.The clinical treatment of this disease is generally surgery,chemotherapy,radiotherapy,etc.However,radiochemical therapy causes great damage to the body,and most patients cannot tolerate it.Traditional Chinese medicine can conduct comprehensive interventions from multiple perspectives,multiple channels,and individualization,which is conducive to regulating the body's state,improving immunity,and assisting in improving the therapeutic effect.Peritoneal hyperthermic perfusion therapy has been widely used in gastric cancer,ovarian cancer and other malignant tumors in recent years.It is a method of heating chemotherapy drugs to about 43℃ and infusing them into the abdominal cavity,and adding traditional Chinese medicine to the perfusion solution to promote the drugs through high temperature,the technology of enhanced penetration power,effectively kills off the cancer cells,and prevent cancer cells from metastasis or inactivate them,which is beneficial to improve the therapeutic effect.The author reviewed many studies and summarized the feasibility of traditional Chinese medicine combined with abdominal hyperthermia in the treatment of colorectal cancer.
作者 王济国 石卫东 WANG Jiguo;SHI Weidong(Department of Oncology,Shenzhen Baoan Hospital of Traditional Chinese Medicine(Group),Shenzhen,Guangdong Province,518133 China;Department of Integrated Traditional Chinese and Western Medicine,Affiliated Tumor Hospital of Fudan University,Shanghai,200032 China)
出处 《中外医疗》 2021年第19期194-198,共5页 China & Foreign Medical Treatment
关键词 腹腔热灌注 中医药联合 综述 结直肠癌 Intraperitoneal hyperthermic perfusion Combination of traditional Chinese medicine Review Colorectal cancer
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