摘要
目的研究补肺化浊汤联合穴位贴敷治疗慢性阻塞性肺疾病(COPD)缓解期的临床效果。方法选取2020年3—12月于抚州市中医院就诊的60例COPD缓解期患者作为研究对象,按照随机数字表法将其分为对照组与试验组,每组各30例。对照组患者给予噻托溴铵粉吸入剂,试验组患者给予补肺化浊汤及穴位贴敷治疗,两组患者均连续治疗8周。比较两组患者治疗前后的疗效、肺功能、呼吸困难程度、生活质量、血液流变学指标。结果试验组患者的总有效率(83.3%)高于对照组(73.3%),差异有统计学意义(P<0.05)。治疗前,两组患者的用力肺活量(FVC)、第1秒用力呼气容积(FEV_(1))及FEV_(1)占预计值百分比(FEV_(1)%)水平比较,差异无统计学意义(P>0.05);治疗后,两组患者的FVC、FEV_(1)及FEV_(1)%水平均高于治疗前,差异有统计学意义(P<0.05);治疗后,试验组患者的FVC、FEV_(1)及FEV_(1)%水平高于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者的改良版英国医学研究委员会呼吸问卷(mMRC)、慢性阻塞性肺疾病评估测试(CAT)得分比较,差异无统计学意义(P>0.05);治疗后,两组患者的mMRC、CAT得分均低于治疗前,差异有统计学意义(P<0.05);治疗后,试验组患者的mMRC、CAT得分低于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者的高切全血黏度、中切全血黏度、低切全血黏度、血浆黏度水平比较,差异无统计学意义(P>0.05);治疗后,两组患者的高切全血黏度、中切全血黏度、低切全血黏度、血浆黏度水平均低于治疗前,差异有统计学意义(P<0.05);治疗后,试验组患者的高切全血黏度、中切全血黏度、低切全血黏度、血浆黏度水平低于对照组,差异有统计学意义(P<0.05)。结论补肺化浊汤联合穴位贴敷能够缓解COPD缓解期患者的临床症状及改善血液流变学指标,从而改善患者的肺功能,提高患者的生活质量。
Objective To study the clinical effect of Bufei Huazhuo Decoction combined with acupoint application in the treatment of chronic obstructive pulmonary disease(COPD)in remission.Methods A total of 60 COPD patients who came to Fuzhou Hospital of Traditional Chinese Medicine from March 2020 to December 2020 were selected as the rasearch objects,and they were divided into the control group and the test group according to the random number table method,with 30 cases in each group.The patients in the control group were given Tiotropium Bromide Powder Inhalation,and the patients in the test group were given Bufei Huazhuo Decoction and acupoint application treatment.Patients in both groups were treated for 8 weeks.The symptom scores,lung function,dyspnea,quality of life,blood rheology indexes before and after treatment were compared between the two groups.Results The total effective rate of the test group(83.3%)was higher than that of the control group(73.3%),and the difference was statistically significant(P<0.05).There were no statistically significant differences in the levels of forced vital capacity(FVC),forced expiratory volume in the 1 second(FEV_(1))and FEV_(1) as a percentage of predicted value(FEV_(1)%)between the two groups before treatment(P>0.05).The FVC,FEV_(1) and FEV_(1)%levels of the two groups of patients after treatment were higher than those before treatment,and the differences were statistically significant(P<0.05).The FVC,FEV_(1) and FEV_(1)%of the test group after treatment were higher than that of the control group,and the differences were statistically significant(P<0.05).There were no statistically significant differences in the scores of the modified British Medical Research Council respiratory questionnair(mMRC)and the chronic obstructive pulmonary disease assessment test(CAT)between the two groups before treatment(P>0.05).After treatment,the scores of mMRC and CAT of the two groups were lower than those before treatment,and the differences were statistically significant(P<0.05).After treatment,the scores of mMRC and CAT of the test group were lower than those of the control group,and the differences were statistically significant(P<0.05).There were no statistically significant differences in high-cut whole blood viscosity,mid-cut whole blood viscosity,low-cut whole blood viscosity and plasma viscosity before treatment(P>0.05).After treatment,high-cut whole blood viscosity,mid-cut whole blood viscosity,low-cut whole blood viscosity and plasma viscosity of the two groups were lower than those before treatment,and the differences were statistically significant(P<0.05).After treatment,high-cut whole blood viscosity,mid-cut whole blood viscosity,low-cut whole blood viscosity and plasma viscosity of the test group were lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusion Bufei Huazhuo Decoction combined with acupoint application can alleviate the clinical symptoms and hemorheology of patients with COPD in remission,while reducing the number of acute attacks,thereby improving patients′lung function and improving their quality of life.
作者
何伟建
肖卫
胡小花
刘冲顺
张萍
黄纡寰
HE Wei-jian;XIAO Wei;HU Xiao-hua;LIU Chong-shun;ZHANG Ping;HUANG Yu-huan(Departmen of Pulmonary Diseases,Fuzhou Hospital of Traditional Chinese Medicine,Jiangxi Province,Fuzhou 344000,China)
出处
《中国当代医药》
CAS
2021年第25期187-190,共4页
China Modern Medicine
基金
江西省抚州市社会发展指导性科技计划项目(抚科计字【2020】10号59)。
关键词
慢性阻塞性肺疾病
补肺化浊汤
穴位贴敷
肺功能
Chronic obstructive pulmonary disease
Bufei Huazhuo Decoction
Acupoint application
Lung function
