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乳腺癌患者血清IL-6、IL-8、肿瘤坏死因子-α水平变化及其临床意义 被引量:3

Changes of Serum IL-6,IL-8 and TNF-αLevels in Breast Cancer Patients and their Clinical Significance
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摘要 目的:对乳腺癌患者血清IL-6、IL-8、TNF(肿瘤坏死因子)-α水平的变化进行分析评价。方法:2019年1月—2020年12月,选择58例乳腺癌患者,其中早期31例,晚期27例,并选择28例健康者,对所有人进行血清IL-6、IL-8、TNF-α水平检测,分析三组血清IL-6、IL-8、TNF-α水平。结果:与健康者进行比较,早期和晚期IL-6、IL-8、TNF-α水平均高,与早期比较,中期IL-6、IL-8、TNF-α水平高。结论:通过IL-6、IL-8、TNF-α水平可以反映乳腺癌手否处于活动期,对乳腺癌病情的判断和预后,具有重要的临床价值。 Objective: To analyze and evaluate the changes of serum IL-6, IL-8 and TNF-α levels in breast cancer patients.Methods: From January 2019 to December 2020, 58 patients with breast cancer were selected, including 31 patients at early stage and 27 patients at late stage, and 28 healthy people were selected. Serum levels of IL-6, IL-8, and TNF-α were detected in all people, and the levels of serum IL-6, IL-8, and TNF-α in the three groups were analyzed. Results: Compared with healthy people, the levels of IL-6, IL-8 and TNF-α were higher in the early and late stages. Compared with the early stage, the levels of IL-6, IL-8 and TNF-α were higher in the middle stage. Conclusion: The level of IL-6, IL-8 and TNF-α can reflect whether breast cancer is in the active phase, and it has important clinical value for the judgment and prognosis of breast cancer.
作者 林曼 LIN Man(Nanshan District Maternity and Child Health Hospital,Shenzhen,Guangdong,518067,China)
出处 《黑龙江医学》 2021年第17期1833-1834,共2页 Heilongjiang Medical Journal
关键词 乳腺癌 IL-6 IL-8 肿瘤坏死因子-Α 早期 晚期 Breast cancer IL-6 IL-8 TNF-α Early stage Advanced stage
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