摘要
目的探究尿微量白蛋白(albumin,U-mAlb)、糖化血红蛋白(glycosylated hem oglobin Alc,HbAlc)、血清胱抑素C(cystatin C,CysC)在糖尿病患者早期肾损伤中的临床应用效果。方法选取2020年1—12月期间于该院就诊的50例糖尿病患者作为研究对象,根据其肾脏功能是否受损分为A组(糖尿病合并肾损伤患者,23例)、B组(单纯糖尿病患者,27例),另选择同期入院进行健康检查的25名健康体检者作为对照组,对3组的U-mAlb、HbAlc、CysC进行检测并比较,同时比较3组上述指标的阳性率。结果A组的U-mAlb、HbAlc、CysC水平均高于B组、对照组,差异有统计学意义(P<0.05);B组的U-mAlb、HbAlc、CysC水平均高于对照组,差异有统计学意义(P<0.05);A组的U-mAlbmAlb、HbAlc、CysC的检测阳性率均高于B组、对照组,差异有统计学意义(P<0.05),对照组的3项指标检测均为阴性。结论U-mAlb、HbAlc、CysC在糖尿病患者早期肾损伤诊断中具有较高的临床价值,3项指标可以反映患者的肾损伤情况,提高早期肾损伤的检出率,有助于患者的早期治疗。
Objective To explore the clinical effects of urinary microalbumin(albumin,U-mAlb),glycosylated hem oglobin Alc(HbAlc),and serum Cystatin C(cystatin C,CysC)in early renal injury in diabetic patients.Methods Fifty patients with diabetes who were treated in the hospital from January to December 2020 were selected as the research objects.According to whether their kidney function was damaged,they were divided into group A(patients with diabetes and kidney injury,23 cases)and group B(simple diabetes patients,27 cases),and 25 healthy people who were admitted to the hospital for health checkups during the same period were selected as the control group.The U-mAlb,HbAlc,and CysC of the three groups were tested and compared,and the positive rates of the three groups were compared at the same time.Results The levels of U-mAlb,HbAlc,and CysC in group A were higher than those in group B and the control group,and the difference was statistically significant(P<0.05);the levels of U-mAlb,HbAlc and CysC in group B were higher than those in the control group,and the difference was statistically significant(P<0.05).The positive rate of U-mAlb and HbAlc,CysCin in group A was higher than that of group B and the control group,and the difference was statistically significant(P<0.05).The three indicators of the control group were all negative.Conclusion U-mAlb,HbAlc,and CysC have high clinical value in the diagnosis of early renal injury in diabetic patients.The three indicators can reflect the patient's renal injury,improve the detection rate of early renal injury,and contribute to the early treatment of patients.
作者
李艾英
LI Aiying(Department of Laboratory Medicine,Jiawang District People's Hospital,Xuzhou,Jiangsu Province,221011 China)
出处
《糖尿病新世界》
2021年第14期17-20,共4页
Diabetes New World Magazine
