摘要
目的探讨经尿道前列腺钬激光剜除术(HoLEP)与经尿道前列腺电切术(TURP)治疗良性前列腺增生的临床效果。方法方便选择该院2020年1月—2021年1月收治的80例良性前列腺增生患者为研究对象,以随机数字表法分为两组,各40例,对照组行TURP治疗法,观察组采用HoLEP治疗法,比较两组患者的手术时间、术中出血量、前列腺症状评分(IPSS)、生活质量评分(QOL)、最大尿流率(Qmax)、残余尿(PVR)以及尿道狭窄发生率。方法观察组手术时间(79.65±8.13)min长于对照组(65.39±8.69)min,差异有统计学意义(t=7.579,P<0.001);术中出血量(122.36±15.24)mL小于对照组(189.63±20.13)mL,差异有统计学意义(t=16.851,P<0.01);术后3个月,两组IPSS评分、QOL评分、Qmax、PVR参数均改善,且观察组IPSS评分(8.35±0.66)分低于对照组(9.01±1.18)分,差异有统计学意义(t=3.087,P=0.003);QOL评分(1.65±0.41)分低于对照组(1.84±0.38)分,差异有统计学意义(t=2.150,P=0.035);Qmax(20.65±3.34)mL/s大于对照组(18.69±2.69)mL/s,差异有统计学意义(t=2.891,P=0.005);PVR(32.41±2.52)mL小于对照组(34.65±3.23)mL,差异有统计学意义(t=3.458,P=0.001);观察组尿道狭窄发生率(2.50%),低于对照组(20.00%),差异有统计学意义(χ^(2)=4.507,P=0.034)。结论对于良性前列腺增生患者,HoLEP手术方式虽然延长手术时间,却降低了术中出血量,减小对患者机体创伤,患者生活质量高,不良反应小,恢复速度较快,值得临床推广。
Objective To investigate the clinical effects of transurethral holmium laser enucleation of the prostate(HoLEP)and transurethral resection of the prostate(TURP)in the treatment of benign prostatic hyperplasia.Methods Eighty patients with benign prostatic hyperplasia admitted to the hospital from January 2020 to January 2021 were convenient selected as the research objects.They were divided into two groups by random number table method,40 cases in each group.The control group was treated with TURP and the observation group was treated with HoLEP,compare the operation time,intraoperative blood loss,prostate symptom score(IPSS),quality of life score(QOL),maximum urine flow rate(Qmax),residual urine(PVR)and incidence of urethral stricture between the two groups.Results The operation time of observation group was(79.65±8.13)min longer than that of control group(65.39±8.69)min,the difference was statistically significant(t=7.579,P<0.001);intraoperative blood loss(122.36±15.24)mL was less than that of control group(189.63±20.13)mL,the difference was statistically significant(t=16.851,P<0.01);3 months after the operation,the IPSS score,QOL score,Qmax,and PVR parameters of the two groups improved,and the IPSS score(8.35±0.66)of the observation group was lower than control group(9.01±1.18)points,the difference was statistically significant(t=3.087,P=0.003);QOL score(1.65±0.41)points lower than control group(1.84±0.38)points,the difference was statistically significant(t=2.150,P=0.035);Qmax(20.65±3.34)mL/s was greater than the control group(18.69±2.69)mL/s,the difference was statistically significant(t=2.891,P=0.005);PVR(32.41±2.52)mL was smaller than the control group(34.65±3.23)mL,the difference was statistically significant(t=3.458,P=0.001);the incidence of urethral stricture in the observation group was 2.50%,which was lower than 20.00%in the control group,the difference was statistically significant(χ^(2)=4.507,P=0.034,P<0.05).Conclusion For patients with benign prostatic hyperplasia,although the HoLEP surgical method prolongs the operation time,it reduces the amount of intraoperative blood loss and reduces the trauma to the patient's body.The quality of life of the patient is high,the adverse reaction is small,and the recovery speed is faster.It is worthy of clinical promotion.
作者
刘继普
钟煜韡
郑永宏
张碧如
LIU Jipu;ZHONG Yuwei;ZHENG Yonghong;ZHANG Biru(Department of Urology,Huizhou Sixth People's Hospital,Huizhou,Guangdong Province,516211 China)
出处
《中外医疗》
2021年第21期85-88,共4页
China & Foreign Medical Treatment
基金
惠州市科技计划项目(200417114573551)。
关键词
良性前列腺增生
前列腺症状
生活质量
Benign prostatic hyperplasia
Prostate symptoms
Quality of life
