摘要
越来越多的研究表明,肠道菌群可以通过修饰食物致敏原、调节肠黏膜免疫平衡及屏障功能影响食物过敏的发生和发展。本文综述了饮食结构及膳食成分对肠道菌群的影响,并在此基础上讨论肠道菌群变化与肠上皮免疫反应的关系,揭示膳食成分通过调控肠道特异性微生物影响食物过敏的作用机制。通过了解膳食成分对肠道微生物的调控规律,能够明确饮食习惯及膳食结构在食物过敏发生发展中所起的作用,从而为食物过敏人群提供科学的膳食指导。
A growing body of research suggests that intestinal flora can affect the occurrence and development of food allergies by modifying food allergens and regulating intestinal mucosal immune balance and barrier function.This article reviews the effects of dietary structures and components on intestinal microflora,discusses the relationships between the changes of intestinal microflora and intestinal epithelial immune response and reveals the mechanism of action by which dietary components affect food allergy by specifi cally regulating intestinal microorganisms.Understanding the regulatory effect of dietary components on intestinal microorganisms is of great signifi cance to clarify the role of dietary habits and structure in the occurrence and development of food allergies and more broadly to provide scientifi c dietary guidance for people with food allergies.
作者
刘翼翔
马玉
李东慧
王彦波
傅玲琳
刘光明
LIU Yixiang;MA Yu;LI Donghui;WANG Yanbo;FU Linglin;LIU Guangming(College of Food and Biological Engineering,Jimei University,Xiamen 361021,China;School of Food Science and Biotechnology,Zhejiang Gongshang University,Hangzhou 310018,China)
出处
《食品科学》
EI
CAS
CSCD
北大核心
2021年第17期282-290,共9页
Food Science
基金
“十三五”国家重点研发计划重点专项(2019YFC1605003-3)。
关键词
膳食结构
膳食成分
食物过敏
肠道菌群
dietary structure
dietary composition
food allergy
intestinal flora
