摘要
目的研究PDCA模式在恶性脑胶质瘤患者化疗中的作用。方法将102例恶性脑胶质瘤化疗患者按随机数字表法分为常规组与研究组,每组51例,常规组采用常规化疗,研究组应用PDCA模式化疗。比较两组患者临床总有效率、治疗依从率、用药知晓率,观察两组患者管理前后的自我管理能力、生活质量与生活能力评分,评估两组患者化疗的不良反应发生情况。结果研究组患者临床总有效率、治疗依从率、用药知晓率均明显高于常规组患者,差异均有统计学意义(P﹤0.01)。管理前,两组患者自我管理能力各维度评分、Barthel指数评分与健康调查简表(SF-36)评分比较,差异均无统计学意义(P﹥0.05);管理后,研究组患者自我管理能力各维度评分、Barthel指数评分与SF-36评分均明显高于常规组,差异均有统计学意义(P﹤0.01)。治疗期间,研究组患者胃肠道系统、血液系统、神经系统、骨髓抑制不良反应发生程度均明显低于常规组,差异有统计学意义(P﹤0.01)。结论PDCA模式能够提高恶性脑胶质瘤化疗的临床总有效率,增强患者的自我管理能力及对治疗的依从性,改善患者生活质量。
Objective To study the effect of PDCA mode on malignant glioma patients undergoing chemotherapy.Method A total of 102 patients receiving malignant glioma chemotherapy were divided into the routine group and study group according to the random number table method,with 51 cases in each group.The routine group was treated with conventional chemotherapy,and the study group was treated with PDCA mode chemotherapy.The total clinical response rate,treatment compliance rate,and medication awareness rate of the two groups of patients were compared.The self management ability,quality of life,and daily living ability scores of the two groups before and after management were ob-served.The adverse events of the two groups of patients were also evaluated.Result The total clinical response rate,treatment compliance rate,and medication awareness of patients in the study group were significantly higher than those in the routine group,the differences were statistically significant(P<0.01).Before the management,there was no statistical-ly significant difference between the two groups of patients’self-management ability,Barthel index score,and the MOS item short from health survey(SF-36)score(P>0.05).After the management,the scores of all dimensions of self-man-agement ability,Barthel index and SF-36 scores in the study group were significantly higher than those of the routine group,the differences were statistically significant(P<0.01).During the treatment period,the adverse events of the gastro-intestinal system,blood system,nervous system,and bone marrow suppression in the study group were significantly low-er than those in the routine group,the differences were statistically significant(P<0.01).Conclusion The PDCA model could improve the total clinical response rate of chemotherapy for malignant glioma,enhance the patient’s self-manage-ment competence and compliance with treatment,and improve the patient’s life quality.
作者
丁艳萍
吴瑾
姚艳红
DING Yanping;WU Jin;YAO Yanhong(Department of Neurosurgery,He’nan Provincial People’s Hospital,He’nan Provincial Cerebrovascular Disease Hospital,Zhengzhou University People’s Hospital,Zhengzhou 450003,He’nan,China)
出处
《癌症进展》
2021年第15期1597-1601,共5页
Oncology Progress
