摘要
目的应用数据挖掘方法分析杨廉方教授治疗腰椎间盘突出症的用药规律,为临床治疗腰椎间盘突出症提供参考。方法收集杨廉方教授治疗腰椎间盘突出症的病例,对符合纳入标准的病例进行统计分析。采用Excel 2019统计药物的使用频次及分类,采用SPSS22.0软件对药物进行聚类分析,采用SPSS Modeler18.0软件进行关联规则分析。结果共153份病例符合纳入标准,共使用中药125味,用药频次共计2 136次,其中使用频次≥30次的药物27种,使用频数最高的3味中药为生地黄、杜仲、茯苓;常用药对为山茱萸与山药、生地黄与山茱萸、牡丹皮与山药等;用药以补虚药、祛风湿药、清热药为主,药物归经主要为肝、肾、脾经。结论杨廉方教授治疗腰椎间盘突出症以补益肝肾为主,辅以活血化瘀、健脾利湿,六味地黄丸、独活寄生汤为基础治疗方剂。
Objective: To analyze the medication rules of Prof. Yang Lianfang for lumbar disc herniation based on data mining and to provide the references for the clinical treatment. Methods: Prescriptions for lumbar disc herniation treated by Prof. Yang Lianfang were collected and sorted. Statistical analysis was conducted on the traditional Chinese medicine used in the cases meeting the inclusion criteria. The Excel 2019 was used to calculate medication frequency and medicine attributes. SPSS 22.0 software was used to conduct system clustering analysis.SPSS Modeler 18.0 software was used to analyze the association rules. Results: A total of 153 cases were included according to the inclusion criteria,125 TCM herbs were used,with a total frequency of 2 136 kinds,in which 27 kinds with no less than 30 times of frequency. Rehmannia Recens,Cotex Eucommiae and Poria were the three most frequently used traditional Chinese medicines. The common drug pairs were Corni Fructus and Rhizoma Dioscoreae,Rehmannia Recens and Fructus Corni,Cortex Moutan and Rhizoma Dioscoreae. The main drugs used in the treatment of lumbar disc herniation were tonic drugs,wind dampness removing drugs and heat-clearing medicinal herbs. The main channels of medicine were liver,kidney and spleen. Conclusion: The treatment principle of Prof. Yang Lianfang for lumbar disc herniation are to nourish liver and kidney,active blood and resolve stasis,fortify the spleen and drain dampness. Liuwei Dihuang Pills and Duhuo Jisheng Decoction are used as the basic formula for the treatment of lumbar disc herniation.
作者
左世国
庹绍彬
马成
向昱阳
Zuo Shiguo;Tuo Shaobin;Ma Cheng;Xiang Yuyang(Hunan University of Chinese Medicine,Hunan,Changsha 410208,China)
出处
《中国中医急症》
2021年第9期1537-1540,共4页
Journal of Emergency in Traditional Chinese Medicine
基金
国家卫健委医药卫生科技发展项目(WA2020HK02)
重庆市科卫联合项目(2020ZY023683.2021ZY023671)。
关键词
腰椎间盘突出症
杨廉方
名老中医
数据挖掘
用药规律
Lumbar disc herniation
Yang Lianfang
Famous TCM doctor
Data mining
Medication rules
