摘要
阿尔茨海默病(Alzheimer’s disease,AD)是一种起病隐匿且呈进行性发展的神经系统退行性疾病。临床上AD患者主要表现为认知功能障碍(Cognitive Impairment,CI)和精神行为症状(Behavioral and Psychological Symptoms,BPS),并可能伴有日常功能活动障碍等症状。目前,西药疗法为AD患者的主要治疗方法,但此法只可延缓患者病情,且副作用较多。最新研究认为,针刺疗法对于AD患者CI和BPS等症状具有改善作用。因此,本文对近二十五年针刺对比西药改善AD患者CI和BPS的文献进行梳理,将从针刺方法、针刺选穴、治疗时间以及针刺效果等方面进行分析,发现针刺对轻中度AD患者的CI和BPS治疗效果显著,并探讨分析了相应的治疗方案,为针刺治疗AD提供理论指导。
Alzheimer’ s disease(AD) is a neurodegenerative disease with hidden onset and progressive development.Clinical manifestations of AD patients are mainly cognitive impairment(CI) and behavioral and psychological symptoms(BPS),and may be accompanied by the disable activity of daily living and other symptoms.At present,western medicine therapy is the main treatment for AD patients,but this method can only delay the patient’s condition,and there are many side effects.According to the latest research,acupuncture therapy can improve the symptoms such as CI and BPS in AD patients.Therefore,in this paper,the literature on the improvement of CI and BPS in AD patients by acupuncture compared with western medicine in the past 25 years is reviewed,and the acupuncture methods,acupuncture points selection,treatment time and acupuncture effect are analyzed.It is found that acupuncture has a significant effect on CI and BPs in mild to moderate AD patients,and discusses and analyzes the corresponding treatment scheme,so as to provide theoretical guidance for acupuncture treatment of AD.
作者
刘珂
缪林清
蒋鹭莲
赵丽萍
雒紫寓
池雯欣
朱翔宇
Liu Ke;Miao Linqing;Jiang Lulian;Zhao Liping;Luo Ziyu;Chi Wenxin;Zhu Xiangyu(School of Acupuncture-Moxibustion and Tuina,Beijing University of Chinese Medicine,Beijing 100029,China;Beijing University of Technology,Beijing 100081,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2021年第6期2105-2115,共11页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金委员会青年项目(81803856):基于UPR信号通路探讨针刺对EAE模型小鼠的神经保护作用,负责人:缪林清。
关键词
阿尔茨海默病
针刺
认知功能障碍
精神行为症状
Alzheimer’s disease
Acupuncture
Cognitive impairment
Behavioral and psychological symptoms
